Medline Repository

CREATINE PHOSPHOKINASE --> lactate dehydrogenase

PMID
Sentence
Species
6042689 Thyrotropin and propylthiouracil-induced stimulation of thyroidal creatine phosphokinase and lactic dehydrogenase in the rat. Rats
1190615 The serum glutamic oxaloacetic transaminase, lactic dehydrogenase, and creatine phosphokinase activities were increased in 90, 81, and 38 per cent of the patients, respectively, and the individual values correlated poorly with the arterial PO2. Human
1196129 The combined conditions of myocardial infarction + diabetes led to substantial increases in serum creatine phosphokinase (CPK) and glutamic oxaloacetic transaminase (SGOT) whereas the enzymes glutamic pyruvic transaminase (SGPT) and lactic dehydrogenase (LDH) were reduced. Rats
1197919 In a previous study, the efflux of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) which takes place from isolated mouse skeletal muscle was shown to be significantly reduced by pretreatment of the intact animal with diethylstilbestrol (DES). Mice
1197919 Thus two agents are now known which lower the efflux of CPK and LDH from isolated skeletal muscle. unknown
1197931 It was previously shown that the efflux of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) from isolated mouse gastrocnemius was reduced 20% by a daily dose of 10 mug of diethylstilbestrol (DES) given for 14 or 21 days. Mice
1197931 The present study was designed to ascertain to what degree increasing doses of DES could suppress the CPK and LDH efflux from isolated skeletal muscle, and if DES affected heart in a similar manner. unknown
1197931 The spontaneous efflux of CPK and LDH from the isolated gastrocnemius and heart was then compared in control and treated mice. unknown
1197931 The reduction in efflux was partially dose-dependent: increasing doses up to 100 mug DES per day, progressively reduced skeletal muscle efflux of CPK to 50% and LDH to 30%; higher doses had no additional effect. unknown
940014 The myopathy was characterized by weakness of facial and proximal limb muscles, increased serum concentrations of lactic dehydrogenase and creatine phosphokinase, and histologic evidence of inflammation and degeneration of muscle fibers. Human
773198 Postoperative electrocardiograms and blood levels of serum creatine phosphokinase (CPK), lactic dehydrogenase (LDH), and serum glutamic oxalacetic transaminase (SGOT) were compared in the two groups. Human
773198 No apparent difference was noted in the number of patients with significantly elevated levels of CPK, LDH, or SGOT or in the number with positive isoenzyme patterns of CPK and LDH. unknown
773198 Moreover, there was no significant difference in the mean values of CPK, LDH, or SGOT between the two groups. unknown
940014 The myopathy was characterized by weakness of facial and proximal limb muscles, increased serum concentrations of lactic dehydrogenase and creatine phosphokinase, and histologic evidence of inflammation and degeneration of muscle fibers. Human
966312 Effect of acute carbon monoxide poisoning on serum lactate dehydrogenase and creatine phosphokinase. Rats
966312 Serum lactate dehydrogenase (LDH) activity peaked at 117% above control 2 hr postexposure, while serum creatine phosphokinase (CPK) activity was maximal at 132% above control immediately following termination of exposure. unknown
966312 Serum LDH activity declined to control within 8 hr, while serum CPK undershot controls at 8 hr and returned to the control value by 24 hr. unknown
773198 Postoperative electrocardiograms and blood levels of serum creatine phosphokinase (CPK), lactic dehydrogenase (LDH), and serum glutamic oxalacetic transaminase (SGOT) were compared in the two groups. Human
773198 No apparent difference was noted in the number of patients with significantly elevated levels of CPK, LDH, or SGOT or in the number with positive isoenzyme patterns of CPK and LDH. unknown
773198 Moreover, there was no significant difference in the mean values of CPK, LDH, or SGOT between the two groups. unknown
911095 Depth of needle insertion, pressures, refractive index, rapid reagent strip test (protein, glucose, blood, pH) results, cell counts, content of protein, glucose, sodium, potassium, chloride, calcium, phosphorus, urea nitrogen, and cholesterol, and activities of creatine phosphokinase, aspartate transaminase, lactic dehydrogenase, and alkaline phosphatase were determined. Horses
738928 Creatine phosphokinase and lactate dehydrogenase activities were increased, suggesting muscle damage. Dolphins
743693 Effect of substrates and of coronary artery ligation on mechanical performance and on release of lactate dehydrogenase and creatine phosphokinase in isolated working rat hearts. Rats
743693 Glucose and fatty acid substrates had different effects on the cardiac output, heart work and rates of release of lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) from isolated perfused working rat hearts with coronary artery ligation. unknown
743693 Release of LDH or CPK was increased in hearts perfused with free fatty acids (FFA) instead of glucose. unknown
487157 The edema fluid samples which accumulated in the polyethylene tubes were regularly analyzed for Na+ and K+ content, colloid osmotic pressure, lactate dehydrogenase and creatine phosphokinase activity, and 99mTc-albumin radioactivity; the albumin tracer being introduced intravenously at the time of cold-injury. Cats
565245 Acetylcholinesterase (AChE, EC 3.1.1.7), creatine phosphokinase (CPK, EC 2.7.3.2), and lactic dehydrogenase (LDH, EC 1.1.1.27) activities, [3H]leucine incorporation into protein, and total protein of the cultures decreased in a dose-related manner with DPH concentrations of 30 microgram/ml and greater. Chick Embryo
324344 Serial monitoring of the serum isoenzyme patterns of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) in patients suspected of acute myocardial infarction has become a highly sensitive and specific diagnostic method. Human
338192 Serum enzymes, creatine phosphokinase, serum glutamic oxalo-pyruvic transaminase, serum glutamic pyruvic transaminase, lactate dehydrogenase, and blood urea nitrogen levels were elevated in breeder rats. unknown
401006 DBH activity was not elevated in those with liver disorder and did not correlate with serum bilirubin, transaminase, lactic dehydrogenase, alkaline phosphatase or creatine phosphokinase. Human
190869 Actomyosin ATPase, myokinase, CPK and LDH in human fast and slow twitch muscle fibres. Human
190869 The enzyme activities of Mg2+ stimulated ATPase, creatine phosphokinase (CPK), myokinase (MK) and lactate dehydrogenase (LDH) were determined in pooled fast twitch (FT) and slow twitch (ST) human skeletal muscle fibers, dissected out from freeze-dried muscle biopsy material. unknown
190869 In addition, the isozyme patterns of CPK, MK and LDH were studied by means of isoelectric focusing (CPK and MK) and discelectrophoresis (LDH). unknown
190869 A difference was observed between fibre types with respect to the isozyme distribution of MK and LDH, whereas the CPK isozyme pattern was similar in both fibre types. unknown
199045 Percent distribution of slow twitch muscle fibres and activities of Ca2+ and Ng2+ stimulated ATPases, creatine phosphokinase, myokinase, phosphorylase, lactate dehydrogenase (LDH) and distribution of its isozyme LDH-1 were all analyzed in biopsy samples taken from the vastus lateralis muscle. Human
831703 Circulating levels of lactate dehydrogenase, glutamate-oxaloacetate, glutamate-pyruvate transaminase, and creatine phosphokinase, as well as its isoenzymes, were measured to investigate the possibility of myocardial damage during acceleration to high +Gz. Human
831709 Relative post-dive changes in lactate dehydrogenase, creatine phosphokinase, and transaminase levels in plasma do not appear to be sufficiently different to allow a ready distinction in the degree of susceptibility of one nutritionally defined population from the other. unknown
190548 Enzyme activity of lactate dehydrogenase, glutamate-oxalacetate and glutamate-pyruvate transaminase, creatine phosphokinase, cholinesterase, alkaline, acid and prostatic phosphatase and aldolase has been studied in a total of 213 subjects, of whom 97 were of good health, 63 had bone tumors and 53 suffered from osteomyelitis. Human
139680 Serum creatine phosphokinase, aldolase and lactic dehydrogenase may be elevated after exertion. Human
874572 Plasma activities of creatine phosphokinase, lactic dehydrogenase and glutamic oxaloacetic transaminase were significantly elevated in lambs receiving no vitamin E or selenium, whereas these enzyme activities in those receiving only selenium were non-significantly elevated. unknown
145474 The supernatant was analyzed for a number of enzymes, the regenerative patterns of which can be classified into 3 groups: (1) early increase in activity: hexokinase, glucose-6-phosphate dehydrogenase; (2) early decrease in activity with failure to recover to control levels: phosphorylase, phosphofructokinase, alpha-glycerophosphate dehydrogenase; and (3) early decrease followed by return to control levels: lactate dehydrogenase, pyruvate kinase, creatine phosphokinase, adenylate kinase. Rats
346492 Animals were moribund 12 h postchallenge with C. albicans and were found to have the greatest number of organisms in the heart and kidney, severe interstitial myocarditis, and elevated serum levels of blood urea nitrogen, creatine phosphokinase, serum glutamic oxalacetic transaminase, serum glutamic pyruvic transaminase, and lactic dehydrogenase. Candida albicans
Mice
650843 Creatine phosphokinase (CPK), SGOT, and lactic dehydrogenase levels were transiently elevated, but the change was considered significant only in the CPK level after certain types of exercise. Human
692137 It appears that liver function tests rarely became abnormal after major operations, whereas HAL produced an immediate rise of lactic dehydrogenase and transaminase (up to 5--60 times normal value), and creatine phosphokinase (4--15 times normal). Human
707414 A set of linearly related serum survey specimens was analyzed by more than 200 laboratories on four occasions in 1977 for the five enzymes lactate dehydrogenase, aspartate and alanine aminotransferases, creatine phosphokinase, and alkaline phosphatase. Human
33766 The enzymes studied were glutamic oxaloacetic transaminase (SGOT), glutamic pyruvic transaminase (SGPT), lactic dehydrogenase (LDH), alpha-hydroxybutyrate dehydrogenase (alpha-HBDH), gamma-glutamyl transferase (gamma-GT), creatine phosphokinase (CPK), and the myocardial-specific isoenzyme of CPK (CK-MB). Human
33766 Angiography produced no significant elevations in SGOT, SGPT, alpha-HBDH, LDH, or CK-MB activities; gamma-GT increased up to the twelfth hour. unknown
33766 In vitro examinations also showed that concentrations of contrast media used in coronary angiography do not inhibit gamma-GT, LDH, and CPK activities. unknown
442861 To this end we have evaluated the activity of the transaminase (GOT-GPT), malic dehydrogenase (MDH), lactic dehydrogenase (LDH) and creatine phosphokinase (CPK). Human
577443 The hepatic tolerability of phthalazine-(2,2-b)-phthalazin-5,12-(7H,14H)-dione (diftalone--administered at the dosage of 750 mg/day p.o. for a mean period of 23 days--has been studied in 40 patients by means of: total plasma protein, albumin, fibrinogen, serum glutamin-oxalacetic transaminase, serum glutamic-pyruvic transaminase, lactic dehydrogenase, creatine phosphokinase, alkaline phosphatase, glycemic curve after glucagon and plasmatic elimination of bromosulphalein. Human
1162737 Biochemical, immunological and genetic studies in leprosy. I. Changes in serum lactate dehydrogenase isoenzymes, creatine phosphokinase and aldolase activity in different forms of leprosy. Human
1162737 Serum lactate dehydrogenase isoenzymes, creatine phosphokinase and aldolase activity were determined in healthy control subjects and in lepromatous and tuberculoid leprosy patients from Ethiopia. unknown
1172987 Total serum enzyme activity for creatine phosphokinase (CPK), alpha-hydroxybutyric dehydrogenase (HBDH), lactic dehydrogenase (LDH), and serum glutamic oxaloacetic transaminase (SGOT), as well as the isoenzymes of CPK and LDH, were measured on admission and for ten subsequent days in 100 patients admitted consecutively to a coronary care unit. Human
1172987 The combined use of CPK and LDH isoenzyme levels provided the greatest laboratory discrimination between the two clinical groups (MI vs non-MI). unknown
1172987 The routine use of HBDH and SGOT levels can be abandoned in the setting of a coronary care unit if CPK and LDH isoenzyme assays are available. unknown
1269225 A comparison of glutamic-oxalacetate transaminase, lactate dehydrogenase, alpha-hydroxybutyrate dehydrogenase, and creatine phosphokinase activities in non-spawning, pre-spawning, and spawning pink salmon. Dogfish
Human
Salmon
938273 Creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) activities, characteristically high in DMD, and presumably of muscle origin, were reduced significantly (P LESS THAN .05). Human
938273 Experimentally, diethylstilbestrol reduced the efflux of CPK and LDH from mouse skeletal muscle. unknown
938992 Serial blood samples were drawn for 24 h following the beginning of occlusion and were used to determine total and isoenzyme levels of CPK, and lactic dehydrogenase isoenzymes. Dogs
977678 The three iso-enzymes of creatine phosphokinase were separated and assayed in 4 min and the five isoenzymes of lactic dehydrogenase in 6 min. Cattle
Human
Rats
837501 Myocardial depletion of creatine phosphokinase activity (CPK) and lactate dehydrogenase activity (LDH) were determined 24 hours after temporary LCX occlusion. unknown
160447 An increase in heart weight was associated with a change in the ratios of bound to free forms of five lysosomal enzymes, a change in serum creatine phosphokinase and lactate dehydrogenase, and a change in the morphology of the myocardial cells. Rabbits
404802 Half-life times of lactic dehydrogenase isoenzymes, malic dehydrogenase, glutamic-oxaloacetic transaminase and creatine phosphokinase in chicken blood. Chickens
142828 Samples were analysed biochemically for enzyme activity of lactic dehydrogenase (LDH), creatine phosphokinase (CPK), aldolase (ALD), citrate synthase (CS), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) and for glycogen content. Horses
7438477 Plasma creatine phosphokinase and lactate dehydrogenase levels were higher in the presence of an effusion. Human
7442308 Cardiac lymph contained significantly higher concentrations of creatine phosphokinase, lactic dehydrogenase and lactate. unknown
7444927 The changes in the activities of lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) in de blood of thirty-three horses with 'tying up' were compared. Horses
7444927 The extent to which the serum enzymes LDH, CPK and glutamic oxaloacetic transaminase (GOT) and the changes in the activities of these enzymes after suitable labour can be used in the diagnosis of 'tying up' and in following the recovery of patients was studied. unknown
7260911 Primary cultures of rat myocardial cells were used to investigate the dose and time-dependent cellular enzyme release induced by either Adriamycin or daunorubicin, Concentrations of either anthracycline (1.8 or 18 microM) produced significant release of creatine phosphokinase and lactic dehydrogenase from myocardial cells within 24 hr of exposure without a detectable decrease in cell viability. unknown
7140302 Reference (normal) ranges for alkaline phosphatase, total bilirubin, urea nitrogen, chloride, cholesterol, total carbon dioxide, creatine phosphokinase, gamma glutamyl transpeptidase, glucose, lactic dehydrogenase, aspartate and aminotransferase, alanine aminotransferase, sorbitol dehydrogenase and triglycerides were established for cattle, sheep, pigs, ponies and ducks by use of the ABA-100 and A-Gent reagents (Abbott Laboratories). Cattle
Ducks
Horses
Sheep
Swine
6849596 Since calcium levels best correlate inversely with serum myoglobin and lactic dehydrogenase, we suggest that these two enzymes are better markers of the activity of rhabdomyolysis than serum creatine phosphokinase or SGOT. unknown
6657721 While creatine phosphokinase levels were unaffected by either cholinesterase inhibition or exercise in the heat, lactate dehydrogenase activities were increased (p less than 0.01) in both groups following hyperthermic exhaustion. Rats
6672210 Histochemical alterations of acute and chronic doxorubicin (DOX) cardiotoxicity in the mouse were assessed by the localization of succinate dehydrogenase (SDH), coenzyme Q10 (CoQ), cytochrome oxidase (COX), creatine phosphokinase (CPK), lactate dehydrogenase (LDH), reduced glutathione (GSH), and intracellular calcium. Mice
6672210 Altered staining patterns of SDH, CoQ, COX, CPK, and LDH under the chronic protocol were only seen after abnormal staining was evident in trichrome stained sections. unknown
6342116 The circadian rhythms of twenty-one chemical serum parameters (albumin, alkaline phosphatase, calcium, carbon dioxide content, chloride, cholesterol, creatine phosphokinase (CPK), creatinine, glucose, glutamic-oxalacetic transaminase (GOT), gamma glutamyl transferase (Gamma--GT), lactate dehydrogenase (LDH), inorganic phosphorus, iron, potassium, total bilirubin, total protein, sodium, triglycerides, urea nitrogen, uric acid) and of urinary volume and oral temperature were studied, in October 1981, in a group of 49 elderly subjects (23 men, 73 +/- 6 years of age, and 26 women, 77 +/- 8 years of age) institutionalized at the Berceni Hospital for the aged. Human
7284035 Analysis of the enzymatic activities of lactate dehydrogenase, glutamic oxaloacetic transaminase, and creatine phosphokinase failed to reveal any statistically significant differences between the nonexposed controls and those groups exposed to either 5 or 20 mW/cm2. Unknown
7097108 The prognostic value of initial and sequential determinations of quantitative bacterial concentrations, leukocytes, glucose, lactate, lactic acid dehydrogenase, and creatine phosphokinase in CSF was examined in rabbits with experimental pneumococcal meningitis while they were receiving equivalent, rapidly bactericidal antibiotic therapy. Rabbits
7123485 The serum glutamic oxaloacetic transaminase, lactic dehydrogenase, and creatine phosphokinase levels were significantly elevated in patients with nonocclusive ischemia and less elevated in patients with arterial or venous thrombosis. Human
6130168 Activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine phosphokinase (CPK), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) were measured in plasma, liver, and kidney, and gamma-glutamyl transferase (GGT) was measured in liver and kidney of black ducks (Anas rubripes). Ducks
6130168 Activities of ALT, CPK, ALP and GGT were higher in kidney, while LDH was higher in liver, GGT was detected in plasma from one of four mallards. unknown
6854919 Possible myocardium-related enzymes, such as glutamic oxaloacetic transaminase, lactic dehydrogenase and creatine phosphokinase, were elevated within 24 hours and then returned almost to the previous levels. Human
Rats
6141072 Danazol therapy was associated with statistically significant increases in the following serum enzyme levels: creatine phosphokinase, lactate dehydrogenase, serum glutamic oxaloacetic transaminase, and serum glutamic pyruvic transaminase. Human
6144196 Changes of platelets, serum lactic dehydrogenase, gamma-glutamyltranspeptidase, choline esterase and creatine phosphokinase levels in patients with Cushing's syndrome. Human
6144196 Patients with Cushing's syndrome had increased numbers of platelets, moderately elevated serum lactic dehydrogenase and gamma-glutamyltranspeptidase levels, and significantly lower creatine phosphokinase and choline esterase activities compared with those of obese control patients. unknown
7273501 The diagnostic capabilities of this method were compared with those of conventional electrocardiogram and biochemical markers, MB-creatine phosphokinase (MB-CPK) and lactic dehydrogenase (LDH1). Dogs
7273501 Conventional ECG, wideband ECG for PISA analysis, blood samples for LDH1, and MB-CPK were taken before and after 15, 30, 60, and 90 min of acid injection. unknown
7282513 Serum isoenzymes of creatine phosphokinase (CK) and lactate dehydrogenase (LD) were monitored hourly in all groups. Dogs
7282513 These findings suggest that (1) gross and histologic MI size determination of 36 hours after ischemia underestimate extent of damage, and (2) ultrastructural cell changes cause significant release of CK and LD in coronary disease (CAD). unknown
7283514 An analysis of the isoenzymes of creatine phosphokinase and lactic dehydrogenase in the esophagus. Dogs
Human
7283514 Surgical manipulation of muscular organs can cause alterations of the serum isoenzymes of creatine phosphokinase (CPK) and lactic dehydrogenase (LDH), which are frequently used to confirm the diagnosis of myocardial infarction (MI). unknown
7283514 From the study we drew the following conclusions: (1) all three isoenzymes of CPK (including CPK-MB, the myocardialisoenzyme) are present in the esophagus; (2) LDH, the isoenzyme of LDH most prevalent in myocardium, is the least common of the five isoenzymes of LDH in the esophagus; (3) the dog is an appropriate model for studying changes of these isoenzymes after operation; and (4) any potential confusion in diagnosing postoperative MI due to esophageal CPK-MB in the serum can be resolved, theoretically, by analyzing LDH serum isoenzymes. unknown
7305484 Changes in peripheral serum creatine phosphokinase (CPK) and lactic dehydrogenase (LDH) in acute experimental colonic infarction. Dogs
Human
7139878 The release of lactic dehydrogenase, creatine phosphokinase, and aspartate aminotransferase from initially viable, metabolically competent adult rat heart myocytes has been examined. Rats
7139878 Freshly isolated cells contain levels of total lactic dehydrogenase, creatine phosphokinase, and aspartate aminotransferase, as well as lactic dehydrogenase and creatine phosphokinase isoenzyme profiles that are quite comparable to those of intact heart tissue. unknown
7139878 When the cells are lysed with digitonin, 89% of total lactic dehydrogenase, but only 58% of creatine phosphokinase and 27% of aspartate aminotransferase are released. unknown
6860132 Experimental arterial bowel infarction can cause elevations in levels of peripheral serum creatine phosphokinase (CPK), lactic dehydrogenase (LDH), and their isoenzymes. Dogs
6860132 Total CPK and LDH activity were determined by automated spectrophotometry; isoenzyme levels were determined by agarose gel electrophoresis. unknown
3838387 There were blood biochemical alterations with transient elevations of total serum creatine phosphokinase, creatine phosphokinase-MB fraction, aspartate aminotransferase, and lactate dehydrogenase levels at 12 mg/m2, suggesting myocardial damage; however, there was no associated pathologic evidence of cardiotoxicity. Rats
3742891 Clonally derived cell lines from a given tumor differed in their expression of a number of different isozymes, including adenosine deaminase, creatine phosphokinase-B and lactate dehydrogenase. Human
Mice
3619163 The ECG and the determination of serum enzymes creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) may be falsely normal early in acute myocardial infarction. Human
3619163 Myoglobin, an oxygen-carrying protein found in cardiac muscle and striated skeletal muscle, presents an attractive alternative to CPK and LDH in the emergency department setting for identification of acute myocardial infarction. unknown
3353577 A single intraperitoneal injection of doxorubicin (15 mg/kg) produced a significant elevation of calcium and lipoperoxide content at 72 hr, as well as a significant depletion of creatine phosphokinase, glutamic oxaloacetic transaminase and lactate dehydrogenase activities at 48 hr and glutathione peroxidase activity at 24 hr in the myocardium. unknown
3176305 No change was observed in serum aspartate aminotransferase, creatine phosphokinase, lactic dehydrogenase activity, and histologic examination showed no evidence of muscle necrosis. Cassia
Cattle
2774821 In 7 normal healthy Egyptian one-humped camels aged 3-4 years, the relationships were studied between enzyme activities of lactic dehydrogenase (LDH), creatine phosphokinase (CPK), alkaline phosphatase (ALP), acid phosphatase (ACP), and cholonesterase (CHE) of serum and organs as well as between ACP and ALP and between LDH and CPK. Camels
2774821 The following results were obtained: --The heart was the organ with the highest activities of ALP, LDH, and CPK, and it contained high values of CHE, whereas the lowest activities of all enzymes were recorded from serum. unknown
2774821 Strong inverse relationships existed also between serum LDH and kidney LDH as well as between CPK in serum and heart. --Direct relationships were remarkable serum LDH and that of spleen and heart as well as between serum ACP and that of liver and heart. --Interrelationships were inverse between ACP and ALP in liver, kidney, and heart, but weak direct interrelationships were characteristic between the 2 enzymes in serum and spleen. --LDH was inversely interrelated with CPK in serum and heart. unknown
2802077 Acid-base balance, lactate dehydrogenase, creatine phosphokinase, hydroxybutyrate dehydrogenase, oxytocinase and the final products of peroxide oxygenation of lipids-malonate dialdehyde and antioxidant activity were studied on 60 parturients, divided into two groups as each group had 30 women. Human
2802091 We determined the following parameters for evaluation of the metabolic disturbances: alanine aminotransferase, hydroxybutyrate dehydrogenase, lactate dehydrogenase, creatine phosphokinase, alkaline phosphatase, thermostable alkaline phosphatase, oxytocinase and lipid peroxidation. Human
2591985 Blood samples were taken on days -6 and 0 before and on days 4 and 7 after the first BHA administration for the assessment of standard clinical plasma parameters (L-aspartate aminotransferase, L-alanine-aminotransferase, L-gamma-glutamyltranspeptidase, creatine phosphokinase, lactate dehydrogenase, total protein, albumin, urea, creatinine, Na+, and Cl-). Human
2627401 Serum creatine phosphokinase, lactic dehydrogenase, and their isoenzymes in the perioperative period. Human
2627401 The purpose of the present investigation was to determine the normal perioperative variations in the serum concentration of creatine phosphokinase (CPK) and its isoenzymes MM, MB, and BB, and of lactic dehydrogenase (LDH) and its isoenzymes LDH1 to LDH5 to distinguish operation-induced changes in these enzymes from those due to acute myocardial infarction or malignant hyperthermia. unknown
2632387 The myocardial damage was proved by observing the elevated levels of serum aspartate amino-transferase, lactate dehydrogenase and creatine phosphokinase and the changes were confirmed by histopathology of the tissue. unknown
2646099 During 20 weeks blood constituents in peripheral blood (Erythrocyte count, Packed cell volume, Hemoglobin, Sedimentation rate, activities of Aspartate aminotransferase, Alanine aminotransferase, Creatine phosphokinase, Lactate dehydrogenase, Lactate dehydrogenase-1-isoenzyme, Glucose, Lactate, Total bilirubin), pulse and respiration rate were determined at rest and after exercise. Horses
2517498 The loss of creatine phosphokinase and lactate dehydrogenase activities due to an increased ischaemia time was limited in defibrotide-perfused hearts. Rats
2419700 Three-hour reperfusion of the left anterior descending coronary artery, which had been ligated for 3 h, significantly increased cardiac lymphatic release of lactate dehydrogenase (LDH), cathepsin D and creatine phosphokinase (CPK), and the incidence of ventricular premature contractions (VPCs), the increases being markedly higher than those in ligation period. Dogs
3158041 The activities of the glycolytic enzymes - hexokinase, phosphofructokinase, pyruvate kinase and lactate dehydrogenase - were also increased in these glands, whereas the activity of creatine phosphokinase was unchanged. unknown
3158144 Administration of ISP caused increased serum creatine phosphokinase (CPK), lactate dehydrogenase (LDH) and decreased myocardial glycogen, adenosine triphosphate (ATP) creatine phosphate (CP) and glycolysis through phosphofructokinase (PFK). Rats
3235852 Concentrations of total serum N-acetyl-neuraminic acid, carcinoembryonic antigen, ferritin, lactate dehydrogenase, creatine phosphokinase and total proteins were measured in both tumor drainage blood (axillary vein) and in peripheral blood taken during surgery from 44 breast cancer patients. Human
3981741 Activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatine phosphokinase (CPK), and lactate dehydrogenase (LDH) were determined in plasma, kidney, liver, and muscle from five species of captive birds. Birds
3995831 Slight leakage of the muscle enzymes creatine phosphokinase (CPK), mitochondrial glutamic oxaloacetic transaminase (GOT-m), and lactate dehydrogenase (LDH) into the recirculated venous blood occurred in specimens preserved in ice water for six hours, but there was a marked increase in enzyme leakage in the other groups. Dogs
3914413 Serum creatine phosphokinase (CPK), glutamate-oxyloacetate transaminase (GOT), and lactate dehydrogenase (LDH) were increased in the myopathy group compared to the non-myopathy group; serum CPK was 1412.6 +/- 902.6 vs. Human
3914413 The elevated serum CPK, GOT and LDH rapidly decreased to the normal range and muscular strength completely improved within 6 to 13 days after hospitalization, when the serum K level remained below than normal. unknown
2944681 The purpose of this study was to investigate the correlation between: the level of plasma B-EP and the intensity of pain in acute myocardial infarction (AMI); and the B-EP and specific enzymes for AMI serum glutamic oxolo-acetic transferase, lactate dehydrogenase, and creatine phosphokinase and some stress hormones (cortisol, growth hormone). Human
2944681 Significant negative correlation was shown between B-EP and chest pain intensity (0-4 graduation) (r = 0.8, p less than 0.01); lactate dehydrogenase (r = 0.7, p less than 0.01); serum glutamic oxolo-acetic transferase (r = 0.6, p less than 0.01); creatine phosphokinase (r = 0.6, p less than 0.05; plasma cortisol level (r = 0.5, p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS) unknown
2939543 Facial processes of embryonic rats aged 9-15 days were analyzed by isoelectric focusing for their isoenzymic distribution of four enzymes: lactate dehydrogenase, creatine phosphokinase, fructose diphosphate aldolase and phosphoglycerate mutase. Rats
2878107 Creatine phosphokinase (CPK), lactate dehydrogenase (LDH), alkaline phosphatase, aspartate aminotransferase (AAT), calcium, P1 were measured in blood. Human
2878107 The test subjects of the three groups showed a decrease of CPK, LDH, AAT and creatinine. unknown
2878107 Some of the Group 3 subjects who performed regular exercises during the study exhibited smaller decreases of CPK, LDH, AAT and greater stability of calcium and phosphorus. unknown
3029846 Marked alterations in serum enzyme levels, in particular of creatine phosphokinase, lactate dehydrogenase and aldolase occurred in the more severely affected animals. Bluetongue Virus
Sheep
3663911 Creatine phosphokinase and lactate dehydrogenase release from the isolated heart and catecholamine distribution in the heart have been investigated in rats suffering from alcohol withdrawal syndrome. Rats
3691549 Cultured BSC-1 cells were exposed to the mild ionic detergent, Brij 58, and the time course of the release of three enzymes of intermediary metabolism (lactate dehydrogenase, aldolase, and creatine phosphokinase) was determined spectrophotometrically. Unknown
3508562 The local tissue damage after intramuscular injection caused by various commercially available injection solutions was determined in the albino rat, by measuring plasma activities of creatine phosphokinase, aspartate aminotransferase, and lactic dehydrogenase, the tissue activity of creatine phosphokinase, and macroscopic changes in the muscle at the injection site (gastrocnemius muscle). Rats
3508562 The elevations of aspartate aminotransferase (18 hr) and lactate dehydrogenase (2 hr) activity as well as the loss of tissue creatine phosphokinase activity were less indicative of differences between test preparations. unknown
3390652 Reperfusion-induced increases in plasma enzyme activities of lactate dehydrogenase, glutamate-oxaloacetate transaminase and creatine phosphokinase were prevented more effectively when ajmaline was given pre-occlusion rather than post-occlusion. Rats
2903593 Blood vessel walls are shown to contain creatine phosphokinase, lactate dehydrogenase, gamma glutamyl transpeptidase and aspartate transaminase activity. Cattle
3226098 Seven-day exposure to clinostatic and antiorthostatic hypokinesia led to a significant decrease of Krebs cycle enxymes (malate dehydrogenase--MDH and isocitrate dehydrogenase) and creatine phosphokinase with no significant changes in lactate dehydrogenase (LDH), aspartate aminotransferase, alanine aminotransferase and MDH and LDH isoenzymes. Human
2773660 The activities of citrate synthase (CS), 3-OHacyl-coA dehydrogenase (HAD), lactate dehydrogenase (LDH), myokinase (MK) and creatine phosphokinase (CPK) were determined in pools of type I and type II fibres. Human
2573751 In the course of 370-day antiorthostatic (-5 degrees) hypokinesia in which 9 test subjects participated the following changes in serum enzymes associated with energy metabolism inhibition were recorded: decreases of creatine phosphokinase (CPK) at the expense of its MM-isoform, isocitrate and glutamate dehydrogenases as well as increases of alanine and aspartate aminotransferases, gamma-glutamyl transferase, and lactate dehydrogenase (LDH) at the expense of an increased portion of its aerobic H-isoforms. Human
3800794 Clinically affected sheep had higher resting and post-exercise concentrations of serum creatine phosphokinase and lactic dehydrogenase than unaffected control sheep. Sheep
2804095 Fatigue of isolated gastrocnemius muscles from R. pipiens leads to a marked increase in the proportion of phosphofructokinase bound to the particulate fraction and a decrease in the binding of lactate dehydrogenase, pyruvate kinase, creatine phosphokinase and glyceraldehyde-3-phosphate dehydrogenase. Rana pipiens
3971380 EP and MW differed in morphology (spindle-shaped versus round), chromosomal mode (hyperdiploid versus near triploid), estrogen receptor content (43.8 versus 5.1 fmol/mg protein), cloning efficiency (0.24 versus 15%), and activities (milliunits/10(6) cells) of creatine phosphokinase (25.7 versus 62.6) and lactate dehydrogenase (346.7 versus 778.5). Human
3994129 Creatine phosphokinase and lactate dehydrogenase isoenzymes were not detected. Cats
Cattle
Dogs
Horses
4081664 Creatine phosphokinase MB and lactate dehydrogenase isoenzyme 1 in polymyositis. Human
3747812 No consistent differences were found in gross and microscopic morphology, hematocrit and white blood cell counts, plasma creatine phosphokinase, lactic dehydrogenase, cholesterol, triglyceride, or protein concentrations in Magnet groups compared to the two control groups. Mice
2034902 Significantly (P less than 0.05) higher activities of amylase (at 12 hours), lactate dehydrogenase (12 to 48 hours), creatine phosphokinase (12 to 48 hours), aspartate aminotransferase (12 to 24 hours), and gamma-glutamyl transferase (12 to 96 hours) were found in serum samples of acidotic goats. Goats
Wheat
2063732 Moreover, rates of creatine phosphokinase and lactic dehydrogenase release were sharply elevated in the NE hearts but not in those also given ALLO. unknown
1460685 Familiarity with the syndrome, baseline laboratory values including creatine phosphokinase, lactate dehydrogenase, serum glutamicoxaloacetic transaminase, and complete blood cell count with a differential count, and a high index of suspicion are of the utmost importance in making the diagnosis of neuroleptic malignant syndrome. Human
2139616 Turnover of the sarcoplasmic proteins aldolase, phosphoglycerate mutase, lactate dehydrogenase and creatine phosphokinase isolated from chicken breast muscle was investigated using a pulse labelling technique. Chickens
2402132 The purpose of the study was to investigate the effect of anaerobic exercise on serum enzymes lactate dehydrogenase (LDH), creatine phosphokinase (CPK), and aspartate aminotransferase (AST) on elite junior male (n = 5) and female (n = 5) alpine skiers who ranged in age from 12 to 15 years. Human
1799893 During the perfusion period, creatine phosphokinase (CPK), lactic dehydrogenase (LDH) activity, heart rate (HR), derivative of intraventricular pressure time ratio (dP/dt) and changes in systolic ventricular pressure (SVP), diastolic ventricular pressure (DVP) and in coronary blood flow (CBF) were also evaluated. unknown
1799893 At the end of perfusion period no significant changes in CPK, LDH, HR, dP/dt ratio, SVP, DVP and CBF in comparison with basal values were observed in all groups. unknown
2114718 Venous blood was sampled immediately after the 5 show-jumping contests and was analysed for packed cell volume (PCV), blood lactate, blood glucose (GLU), total plasma protein (TPP), bicarbonate (HCO3-), sodium (Na+), potassium (K+), chloride (Cl-), calcium (Ca2+), serum activities of lactate dehydrogenase (LDH), creatine phosphokinase (CPK), glutamic-oxalacetic transminase (GOT) and gamma glutamyl transferase (gamma GT). Horses
2114718 The analysis of the influence of each of the 3 fixed variables showed that (1) there was no relationship between the PEV variations and the score; (2) there were significant (P less than 0.05) variations induced by the competition in Na+, Ca2+, TPP, LDH and GLU, and (3) there were significant interindividual variations as regards Ca2+, TPP, CPK, gamma GT and PCV with P less than 0.05, LDH with P less than 0.01 and blood lactate with P less than 0.001.(ABSTRACT TRUNCATED AT 250 WORDS) unknown
8322842 Throughout hospitalization and 1 year of outpatient follow-up, this patient displayed an inverse relationship between serum creatine phosphokinase and lactic dehydrogenase levels, and serum calcium levels. Human
8324337 After each incubation, creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) were measured and the myocytes then cultured for an additional 24 h at 37 degrees C to evaluate the recovery of the myocyte beating rate. Rats
8324337 The release of CPK and LDH in the 4 degrees C group showed a three-fold increase compared to the other four groups, with a CPK of 147.2 mIU/flask and a LDH of 487.5 mIU/flask. unknown
8198769 The serum creatine phosphokinase and lactic dehydrogenase levels were normal. Human
2035178 Serum levels of triglycerides (TG), creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) activities were also found to be higher in pest-control operators. Human
Rats
2035178 The data show that total cholesterol and serum TG as well as CPK and LDH activities are increased after chlordane treatment. unknown
2035178 The isoenzyme patterns suggest that an increase in CPK and LDH is related to skeletal muscle. unknown
1610371 Increased levels of blood creatine phosphokinase (CPK), lactate dehydrogenase (LDH) and glutamic oxaloacetic transaminase (GOT) were indicative of aseptic necrosis at the injection site. unknown
5110207 Glutamic oxalacetic transaminase, lactic dehydrogenase, and creatine phosphokinase content in cerebrospinal fluid. Human
5030705 Amniotic fluid creatine phosphokinase (CPK) and lactic dehydrogenase (LDH) in feto-placental damage and intrauterine death. Human
5079085 Isozyme patterns of lactate dehydrogenase, creatine phosphokinase, phosphoglucomutase and aldolase guinea pig tissues during ontogeny. Guinea Pigs
4282615 Lactate dehydrogenase and its isoenzymes, creatine phosphokinase and aldolase in different bovine muscles. Cattle
4937334 Creatine phosphokinase relative to acid phosphatase, lactate dehydrogenase, zinc and fructose in human semen with special reference to chronic prostatitis. Human
1149355 The efflux of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) from each was compared over a 4- to 5-hr period. Mice
1278654 The mean serum urea level was significantly elevated, as were creatine phosphokinase and lactic dehydrogenase. unknown
891515 The effects of prolonged strenous exercise on the plasma concentrations of sodium, potassium, calcium, chloride, bicarbonate, phosphate, albumin, cholesterol, glucose, creatinine, bilirubin, alkaline phosphatase, creatine phosphokinase, lactic dehydrogenase and asparate amino transferase were studied in a group of 26 horses competing in an endurance ride. Horses
899821 The main parameters were vertical velocity during running up the stairs, maximal isometric force of leg extensor muscles, blood lactate concentration after maximal treadmill running test, percentage of fast twitch muscle fibers (% FT fibers), lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) activity in vastus lateralis muscle. Human
899821 The running velocity rather than muscle strength seemed to be more influenced by activity of enzymes LDH and CPK. unknown
436275 Differences between the paired samples from a given individual are discussed with respect to the time of sampling for plasma urea, creatinine, proteins, albumin, calcium, sodium, potassium, cholesterol, uric acid, chloride ions, phosphate, bilirubin, aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, creatine phosphokinase, alkaline phosphatase, hemoglobin and erythrocyte and leukocyte counts. Human
448421 The isolation of edema fluid from cats with cold-induced cerebral edema allowed the study of changes of Na+ and K+ content, lactate dehydrogenase and creatine phosphokinase activity, colloid osmotic pressure and the level of intravenously administered 99mTc-albumin in the edema fluid during a period of hypoxia. Cats
462528 Glucose decreased, whereas lactate, lactic dehydrogenase, and creatine phosphokinase increased by significant amounts in both the drainage fluid and bath. unknown
270552 Cardiac enzyme study in the diagnosis of acute myocardial infarction-simultaneous determinations of creatine phosphokinase isoenzymes and lactate dehydrogenase isoenzymes. Unknown
113624 Activities of alkaline phosphatase (1526 U/l), glutamine oxaloacetate transaminase (30.9 U/l), glutamine pyruvate transaminase (13.7 U/l), lactate dehydrogenase (629 U/l), alpha-hydroxybutyrate dehydrogenase (175 U/l), creatine phosphokinase (227 U/l), gamma-glutamyl transpeptidase (38.7 U/l) and sorbitol dehydrogenase (14.2 U/l), and levels of lysozyme (178 mg/dl), zinc (162 microgram/dl), copper (81.3 microgram/dl) and iron (296.5 microgram/dl) have not previously been reported for this animal. unknown
164698 Lactic dehydrogenase concentrations in serum are increased and fluctuate in the presence of sepsis or respiratory insufficiency: Mean creatine phosphokinase peaks at concentrations higher than those reported in acute myocardial infarction and returns to normal in three days. unknown
1125905 The resting 12-lead electrocardiogram (ECG) and serum concentrations of glutamic oxaloacetic transaminase, lactic dehydrogenase creatine phosphokinase and alpha-hydroxybutyrate dehydrogenase were evaluated before, and at 1 and 20 hours after exercise. Human
1148340 Normal standards were defined in term and preterm infants on precise days of the neonatal period for the following serum enzymes: creatine phosphokinase (CPK), lactate dehydrogenase (LDH), diphosphofructoaldolase (ALD), glutamic-oxalacetic (SGOT) transaminase and glutamic pyruvic transaminase (SGPT), CPK values have reached adult standards at 10 days of life. Human
1080352 The levels of creatine phosphokinase, glutamic oxaloacetic transaminase and lactic dehydrogenase in the coronary sinus blood increased dramatically (P less than 0.05) upon reperfusion after 60 or 90 minutes of occlusion, indicating severe impairment of cell membranes. unknown
1187516 A random sample was then collected for the analysis of amylase and another random sample was collected for the analysis of glutamic oxalacetic transaminase (GOT), creatine phosphokinase (CPK), and lactic dehydrogenase (LDH). unknown
1209002 The evaluation was done in terms of serum transaminases (SGOT and SGPT), serum lactic dehydrogenase (LDH), serum creatine phosphokinase (CPK), cardiac glycogen, and cardiac noradrenaline. Rats
1242666 The evaluation of effects of EPL was based on biochemical assays of the blood serum, including creatine phosphokinase (CPK), a-hydroxybutyrate dehydrogenase (HBD) and free fatty acids (FFA) as well as on histological and histochemical studies of lactic dehydrogenase (LDH) of the heart muscle. unknown
1242666 In rats treated with ethanol alone we found increased CPK and HBD activities, elevation of FFA and lowered activity of LDH. unknown
1244297 The effect of continuous removal of thoracic duct lymph on plasma activities of creatine phosphokinase (PCK), glutamic-oxaloacetic transaminase (PAST); and lactic dehydrogenase (PLDH), uas examined in pentobarbital-anaesthetised dogs over a 5.5-hour period. Dogs
1244297 PCK and PAST declined relative to levels in control dogs while PLDH was unaltered. unknown
1248143 However, there were frequent elevations of serum glutamic-oxaloacetic transaminase (9 out of 17 patients), serum creatine phosphokinase (14 out of 17 patients) and serum lactate dehydrogenase (8 out of 14 patients), indicating presence of damage to muscle fibres. Bees
Human
1258770 Both uninfected and infected animals has elevated levels of serum creatine phosphokinase, lactic dehydrogenase and glutamic oxaloacetic transaminase as well as electrocardiographic abnormalities such as increased amplitude of the ORS complex and flattening or inversion of the T wave. Rabbits
1269099 Repeatedly bred spontaneously hypertensive rats (SHR) were found to have severe hypertension, hyperglycemia, hyperlipidemia, elevated creatine phosphokinase (CPK), serum glutamic oxaloacetic and glutamic pyruvic transaminase (SGOT, SGPT), and lactic dehydrogenase (LDH), as well as high circulating corticosterone levels. Rats
1275626 Serum myoglobin, serum creatine phosphokinase, lactic dehydrogenase, and serum glutamic oxaloacetic transaminase values were used as indicators of muscle injury. Human
971172 Plasma activities of lactic dehydrogenase (LDH), creatine phosphokinase (CPK), glutamic pyruvic transaminase (GPT), and alkaline phosphatase (ALP) were studied, along with hematological changes, in rats suffering from various degrees of experimental decompression sickness (DS). Rats
971172 By 1 h after decompression, LDH and CPK activities were elevated in moderate and severe DS whereas GOT and GPT were elevated only in severe DS. unknown
185384 Serum enzymes, including creatine phosphokinase (CPK), aldolase, glutamic oxaloacetic transaminase (SGOT), and lactic dehydrogenase (LDH), decreased initially during high dose systemic corticosteroid therapy, although profound muscle weakness persisted. Human
986587 The affected rats had a marked elevation of plasma creatine phosphokinase (including MB isoenzyme), serum glutamic oxaloacetic transaminase, and lactic dehydrogenase. unknown
941395 The activity of the following enzymes in clinically normal newborn calves was investigated: glutamate-oxalacetate transaminase (GOT), glutamate-pyruvate transaminase (GPT), alkaline phosphatase (APh), creatine phosphokinase (CPhK), lactate dehydrogenase (LDH), leucine-aminopeptidase (LAP), aldolase (A), and cholinesterase (ChE). Cattle
39324 The changes in chemical pathology were in serum transaminases activity (GOT, GPT, GDH); alkaline phosphatase and gamma-glutamyltranspeptidase as indices of cholestasis; lactate dehydrogenase, hydroxybutyrate dehydrogenase and creatine phosphokinase, as enzymes related to energy metabolism; pseudocholinesterase, as a protein metabolism-related enzyme. Human
531558 Myoglobin and the enzymatic activity of creatine phosphokinase CK), MB-isoenzyme of CK (CK-MB), aspartate aminotransferase (GOT), alanine aminotransferase (GPT) and lactic acid dehydrogenase (LDH) were serially determined in 10 patients with acute myocardial infarction. Human
1191441 Five enzymes are used in this study: lactate dehydrogenase (LDH); alpha-hydroxybutyrate dehydrogenase (alpha-HBDH); aspartate aminotransferase (GOT); creatine phosphokinase (CPK); and phosphohexoseisomerase (PHI). Human
877414 The egress of CPK and lactate dehydrogenase from the isolated left gastrocnemius and heart was determined over a 5 hour period. Human
Mice
884869 Only erythrocytes showed a CPK content, however, constantly adjusted to match that of serum as if by free cell membrane passage, but less accomodating to a sudden large influx of CPK than of LDH, where an apparent buffering effect could account for differences in clinical response. unknown
268398 When DES and Pr were given simultaneously to four boys with DMD, the mean creatine phosphokinase and lactate dehydrogenase levels fell to about one half those achieved with either agent alone. Human
906816 Perilymph lactic dehydrogenase (LDH) exhibited differential activity between fetal scalae vestibuli and tympani, and LDH, aldolase, phosphohexose isomerase and creatine phosphokinase in perilymph of particular fetal scalae were elevated in activity in activity in comparison to corresponding maternal values. Guinea Pigs
737243 Isozyme profiles of lactic dehydrogenase and creatine phosphokinase in neonatal mouse hearts. Mice
737243 Isozyme profiles of lactic dehydrogenase (LDH) and creatine phosphokinase (CPK) were determined in cardiac tissue of mice during postnatal development. unknown
570120 The present study was designed to analyze the effects of a short term stress on the quantitative levels of alkaline phosphatase (AP), creatine phosphokinase (CK), aldolase (ALD), lactate dehydrogenase (LDH), and lactate dehydrogenase-1-isoenzyme (LDH 1) during 24 h after stress. Human
Mice
421555 This consisted of elevated total creatine phosphokinase (CPK), an increased myocardial fraction of CPK (myocardial band), alteration in the lactic dehydrogenase isoenzyme pattern, severe bradycardia, and evidence of left ventricular dysfunction. Human
448745 The activity of cardio-specific isoenzymes of creatine phosphokinase and lactate dehydrogenase in monolayer cultures of neonatal rat heart cells. Rats
472963 Creatine phosphokinase and lactate dehydrogenase levels after ultra long-distance running. An analysis of iso-enzyme profiles with special reference to indicators of myocardial damage. Human
491360 Serial tests for the activity of creatine phosphokinase (CPK), specific cardiac isoenzyme MB CPK, lactic dehydrogenase (LDH) and its fractions LDH1 and LDH2 were conducted in 55 patients with myocardial infarction. Human
491365 The article discusses the results of simultaneous tests for the activity of total lactate dehydrogenase (LDH), its isoenzymes and creatine phosphokinase (CPK) in blood serum of 450 patients with macrofocal myocardial infarction; in 213 of them the disease followed a severe course and in 237 a mild course. Human
491365 The authors' study showed that the maximum indices of the activity of LDH, LDH1 fraction and CPK in blood serum were higher in patients with severe myocardial infarction than in those with a mild course of the disease. unknown
362734 New aspects of the clinical value of the determination of isoenzymes of alkaline phosphatase (AP, E.C. 3.1.3.1), creatine phosphokinase (CK, E.C. 2.7.3.2) and lactate dehydrogenase (LDH, E.C. 1.1.1.27) were studied in the following 8 patient groups: 1. Human
7248002 Furosemide-treated animals displayed an increase in circulating levels of creatine phosphokinase, lactic dehydrogenase, free fatty acids, glucose, BUN and uric acid. unknown
7300292 Serum concentrations of myoglobin, creatine phosphokinase and lactic dehydrogenase after exercise in trained and untrained athletes. Human
7091087 Two brothers had intermittent episodes of muscle weakness, lethargy, hyperammonemia, rhabdomyolysis, and elevated activities of creatine phosphokinase (CPK), lactic dehydrogenase, and SGOT in serum associated with low muscle carnitine but normal serum carnitine concentrations. Human
7123134 At the same time with the general morphological study, the activity of the following cellular enzymes in the thyroidian tissue were assayed: lactic dehydrogenase (LDH), glutamic oxalacetate transaminase (GOT), glutamic pyruvate transaminase (CPT) and creatine phosphokinase (CPK). Human
7192280 Blood samples obtained at the same time that rumen samples were obtained showed no treatment effects on serum creatinine, lactic dehydrogenase, alkaline phosphatase, inorganic phosphorus, calcium, creatine phosphokinase, glutamic-pyruvic transaminase or total protein. unknown
7170768 The changes were followed up that take place in the activity of the more important serum enzymes, such as glutamate oxalacetate transaminase, glutamate pyruvate transaminase, serum dehydrogenase, malate dehydrogenase, lactate dehydrogenase, creatine phosphokinase, and alkaline phosphatase, as well as aldolase in the development of the experimental infection with various doses of Taenia ovis eggs in lambs. Sheep
7187815 Effect of preslaughter factors on serum creatine phosphokinase and lactate dehydrogenase enzyme activities in pigs. Swine
7188799 Muscle-associated isoenzymes of creatine phosphokinase and lactic dehydrogenase were increased, but there was no concomitant muscle weakness. unknown
7188799 As the calcium rose, there were corresponding decreases in the serum activities of creatine phosphokinase and lactic dehydrogenase, with correlation coefficients of -0.88 and -0.64, respectively (p less than 0.01). unknown
6978251 Also determined were the specific activities of lactate dehydrogenase, glutamate-oxaloacetate transaminase, glutamate-pyruvate transaminase, and creatine phosphokinase in the extracts of liver from cases of both kinds of hepatic cirrhosis: all of these activities were within the range of control values. Human
6881567 Changes in creatine phosphokinase, lactate dehydrogenase and aspartate aminotransferase activities, possible indices of loss of integrity of muscle cell membranes, varied considerably and did not correlate with the ischemia time. unknown
6626721 Experimental acute myocardial ischemia was accompanied by an increase in blood creatine phosphokinase and lactate dehydrogenase activity as well as by an elevation of serum lactate level and fall of blood plasma calcium concentration, suppression of diuresis and excretion of calcium with urine. Rats
6640385 One case with lightning marks on the abdomen was treated as a crush injury because of myoglobinuria and elevation of serum glutamic oxaloacetic transaminase, lactic dehydrogenase and creatine phosphokinase. Human
6650181 Also 2-3x increases of both serum lactic dehydrogenase (LDH) and creatine phosphokinase (CPK) were noted. unknown
6541488 Rats sacrificed at 12, 24, 30, 36 and 48 h, respectively, after the last injection of ISP showed a marked increase in serum enzymes, viz. creatine phosphokinase (CPK), lactic dehydrogenase (LDH) and aspartate transaminase (AST) and tissue content of lactate. Rats
7353553 Creatine phosphokinase and lactic dehydrogenase levels were abnormally high; blood triglycerides, FFA, glucose, and corticosterone decreased, and total cholesterol, glucose, and corticosterone increased in SD but decreased in SHR rats. Rats
6966486 Serial determinations of serum glutamic oxaloacetic transaminase, lactic dehydrogenase, and creatine phosphokinase were performed in 50 consecutive patients undergoing cardiac operation for coronary artery bypass or combined valve replacement and coronary artery bypass. Human
6769455 The activities in serum of lactate dehydrogenase, alpha-hydroxybutyrate dehydrogenase, aspartate aminotransferase, alanine aminotransferase and creatine phosphokinase and the level of alpha 1-antichymotrypsin increased in a few days after infection. Cercopithecus
Haplorhini
Leptospira interrogans
7406295 Succinylcholine chloride administered to horses anesthetized with halothane in oxygen and mechanically ventilated, caused slight but statistically insignificant (P less than 0.01) increases in creatine phosphokinase, lactic dehydrogenase, and aspartate aminotransferase activity. unknown
7406295 The findings in the present study agree with previous observations on serum creatine phosphokinase, lactic dehydrogenase, and aspartate aminotransferase activity. unknown
7418928 Since muscle dysfunction is frequently associated with a hypothyroid state, many clinical reports have indicated that serum enzyme activities derived from the muscle such as creatine phosphokinase (CPK), lactic dehydrogenase (LDH) and glutamic-oxaloacetic transamynase (GOT) are elevated. Human
7418928 The relationship found between either Mb and LDH or Mb and CPK was also studied in the present study, and it was found that Mb significantly correlated to both LDH and CPK (P<0.001). unknown
6159932 Reduction of serum glutamicoxalacetic transaminase (SGOT), lactate dehydrogenase (LDH), amylase, and creatine phosphokinase (CPK) averaged 17% less, and uric acid, calcium and K+ averaged 53% less than expected. unknown
7204918 Potassium, serum glutamic-oxaloacetic transaminase (SGOT), creatine phosphokinase (CPK), and lactic dehydrogenase (LDH) levels exceeded normal serum values. unknown
7322976 In Trial 2, plasma collected by venipuncture was assayed for creatine phosphokinase (CPK), GOT, glutamic pyruvic transaminase (GPT), and LDH daily from 15 through 19 days of age and for protein at 19 days of age. Unknown
7322976 Significant elevations (P less than or equal to .05) were noted in levels of plasma a) CPK at 15 days, b) GOT at 18 days, and c) LDH at 17 and 19 days. unknown
6671891 Modifications in serum levels of creatine phosphokinase (CPK) lactic dehydrogenase (LDH), glutamic-oxalacetic-transaminases (GOT), glutamic-pyruvic-transaminases, L-gamma-glutamyl transferases, alkaline phosphatase, glycemia, serum nitrogen, creatinine, amylase, sodium and potassium were measured in dogs during experimentally induced acute mesenteric infarction, in the attempt to establish useful criteria for the early diagnosis of mesenteric infarction. Dogs
6671891 Animal with mesenteric infarction displayed a significant increase in serum total CPK, LDH, GOT and alkaline phosphatase. unknown
6678319 In the present study, therefore, in order to diagnose the severity of muscle disorders objectively, serum activities of aldolase (ALD), creatine phosphokinase (CPK) and lactate dehydrogenase (LDH), which are called "muscle enzymes," were determined in 260 chain saw operators aged 40 to 59 years. Human
6678319 However, no relationships were observed between CPK, LDH activities and TOT. unknown
6678319 However, no obvious relationships were found between CPK, LDH activities and numbness and pain symptoms. unknown
6434199 As part of a six-month prospective study of the effects of neonatal thymectomy in the spontaneously diabetic BB Wistar rat, activities of the following enzymes were determined: alkaline phosphatase (AP), lactate dehydrogenase (LDH), creatine phosphokinase (CPK), glutamic-oxaloacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT) and UDP-galactosyltransferase (UDPG). Rats
6480119 High levels of lactate and ammonia in blood had been observed before the elevation of glutamic transaminases, lactic dehydrogenase, and creatine phosphokinase. Human
6517817 Analyses of blood serum collected during and up to 48 h after hypothermia treatments showed elevations at 24 h in creatine phosphokinase (CPK), lactic dehydrogenase (LDH), and glutamic oxaloacetic transaminase (GOT), and these elevations were highest for the ketamine controls and lowest for the RF rewarming experiments. Macaca mulatta
7362350 Sixty-six patients admitted to the coronary care unit within 12 hours of the onset of symptoms of acute myocardial infarction (AMI) were subjected to blood sampling at one- to two-hour intervals for analysis of creatine phosphokinase (CPK) and lactic dehydrogenase (LDH) enzymes and isoenzymes. Human
6448038 Abnormally high levels of plasma creatine phosphokinase, lactate dehydrogenase, and SGOT were found in the untreated dystrophic chickens. unknown
7425715 A comparison of serum isoenzyme levels of creatine phosphokinase and lactic dehydrogenase in patients undergoing thoracic operations and patients admitted to a coronary care unit. Human
7425715 Sera were studied by spectrophotometric analysis (creatine phosphokinase [CPK] and lactic dehydrogenase [LDH]), agarose gel electrophoresis (CPK and LDH), and antibody inhibition spectrophotometric analysis (CPK). unknown
6344411 There were also no consistent changes in the mucosal activities of several enzymes including lactic dehydrogenase, creatine phosphokinase, aldolase, and glutamic oxaloacetate transaminase, whose leakage from damaged or necrotic tissues has been well defined in terms of the concomitant increase in their activity in the circulation. unknown
6087698 Diagnostic tests included the following: serial electrocardiograms (ECG), serial creatine phosphokinase muscle-brain isoenzyme (CPK-MB) and lactic dehydrogenase (LDH) isoenzymes, gated cardiac radionuclide angiography, and technetium-99m (Tc-99m) pyrophosphate scintigraphy. Human
6485684 Quantification of creatine phosphokinase and its isoenzyme MB, serum glutamic oxaloacetic transaminase and lactic dehydrogenase from different sources during aortic valve replacement procedure. Human
6493016 The samples were analyzed for hematocrit (Hct), hemoglobin (Hb), lactate dehydrogenase (LDH), serum glutamic oxalacetic transaminase (SGOT), creatine phosphokinase (CK), CK isoenzymes, and haptoglobin (Hapt). Human
4060176 In both cases, exaggerated elevation of serum levels of the enzymes creatine phosphokinase, lactate dehydrogenase and glutamic-oxaloacetic transaminase were detected, as well as data suggesting acute hypercatabolic renal failure. Human
4060176 In both cases, exaggerated elevation of serum levels of the enzymes creatine phosphokinase, lactate dehydrogenase and glutamic-oxaloacetic transaminase were detected, as well as data suggesting acute hypercatabolic renal failure. Human
3786299 The paper provides representative data on the indices of lipid metabolism and the activity of cardiospecific (lactate dehydrogenase--LDH, creatine phosphokinase--CPK) in patients with diabetes mellitus, Type I and II, (male inhabitants of Kaunas aged 40 to 59) which were compared with similar data on control persons randomly selected from the population during epidemiological surveys. Human
3672921 Studied was the enzyme constellation, resp., activity of alkaline phosphatase (AP), glutamate-oxaloacetic transaminase (GOT), glutamate-pyruvate transaminase (GPT), aldolase (ALD), leucin-aminopeptidase (LAP), cholinesterase (CE), creatine phosphokinase (CPK), lactate dehydrogenase (LDH), ornithine carbamoyltransferase (OCT), and guanase (G) in a total of 360 clinically normal and lactating and dry cows of the Black-and-White and Simmental crossbreeds. Cattle
3672921 Characteristic quantitative changes were found with GOT, GPT, ALD, LDH, and CPK both over the dry period and over the entire period of lactation. unknown
3682091 Bighorn sheep were evaluated for physiological parameters (temperature, pulse and respiration), selected biochemical parameters (cortisol, creatine phosphokinase (CPK), serum glutamic oxaloacetic transaminase (SGOT), lactic dehydrogenase (LDH), alkaline phosphotase (AP), potassium, sodium, chloride, creatinine, blood urea nitrogen (BUN), selenium, glucose, total protein, plasma pH and plasma PCO2), and selected hematological parameters (packed cell volume (PCV), hemoglobin (HB), red blood cell count (RBC), and white blood cell count (WBC]. These parameters were compared among bighorn sheep captured by four different methods: drop-net (n = 158), drive-net (n = 249), chemical immobilization (n = 90) and the net-gun (n = 137). Sheep
3379900 Venous blood and 24-hour urine samples were used to measure Na, K, total and ionized Ca, Mg, total protein, protein fractions, creatinine, urea, uric acid, malate, isocitric and lactate dehydrogenases, aspartate and alanine aminotransferases, and creatine phosphokinase and its isoforms, acid and alkaline phosphatase and its isoenzymes. Human
3172298 Coronary sinus effluent was sampled for pO2, pH, creatine phosphokinase (CPK), and lactic dehydrogenase (LDH). Rats
3172298 LDH and CPK levels were twice as high in Group II as in Group I. unknown
3236641 Lipid, carbohydrate and protein metabolic parameters, such as triglycerides, total and alpha-cholesterol, total protein and albumin, urea nitrogen, creatinine, glucose and the activity of alanine and aspartate aminotransferases, alkaline phosphatase, total lactate dehydrogenase and creatine phosphokinase, were measured in 50 patients with obliterating atherosclerosis and 60 patients with arteritis. Human
2930400 Serum phosphorus, lactate dehydrogenase, and creatine phosphokinase were markedly elevated, whereas potassium, chloride, and calcium values were lowered. Unknown
2712220 Studies of the uteroplacental blood flow and of some peripheral blood enzymes activities in 117 pregnant women have revealed that deterioration of the uteroplacental blood flow is associated with an increase of the activities of hydroxybutyrate and lactate dehydrogenases, creatine phosphokinase, and alkaline phosphatase. Human
3823801 Creatine phosphokinase MB and lactate dehydrogenase isoenzyme 1 and 2 in polymyositis/dermatomyositis. Human
3582624 A structural analogue of gamma-butyrobetaine 3-(2,2,2-trimethylhydrazine)propionate (THP) administered orally in doses of 50 and 150 mg/kg for 10 days prevented isoproterenol-induced increase of the activity of the hepatic isoform of lactate dehydrogenase in the rat blood serum and in a dose of 150 mg/kg prevented an increase of creatine phosphokinase activity. Rats
3342076 The inhibition of fatty acid metabolism at the stage of activation (acyl carnitine formation) can account for the cardioprotective effect of THP, which is assessed by its ability to prevent a decrease in ATP level and myocardial energy charge as well as to prevent a rise in creatine phosphokinase and lactic dehydrogenase (myocardium-specific isozyme) activity in rat blood serum in response to isoproterenol and epinephrine. unknown
2718797 Enzymatic determinations in cerebrospinal fluid (CSF) of lactic dehydrogenase (LDH), creatine phosphokinase (CPK) and creatine kinase BB (CK-BB) were performed on 94 patients presenting with a range of disorders of the central nervous system. Human
2459672 Blood samples for determination of myoglobin, creatine phosphokinase, creatine kinase MB and lactate dehydrogenase were drawn prior to pacing and 1,2,3,4,6,8 and 24 hours after pacing. Human
3096725 Blood samples were analyzed for sodium, potassium, glucose, lactate dehydrogenase, creatinine, creatine phosphokinase, triglycerides, cholesterol, hematocrit, hemoglobin, protein, white blood cell number, uric acid, carbon dioxide, and iron. Human
3096725 After accounting for plasma-volume loss (COR), there remained significant increases in blood serum lactate dehydrogenase, creatinine, creatine phosphokinase, uric acid, iron, and whole-blood white blood cell number. unknown
3096725 Lactate dehydrogenase and creatine phosphokinase concentration changes support the concept of acute damage to muscle tissue resulting from marathon running. unknown
2301606 Perfusion of the rat right ventricular wall muscle for 4 min with a Ca2(+)-free medium followed by perfusion with a Ca2(+)-containing solution resulted in a 42% recovery of developed tension, contracture, and a massive release of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) from the muscle. Rats
2301606 The inclusion of benzamil, an amiloride analogue, 2 min before and during the Ca2(+)-free perfusion period prevented contracture development, restored force development, and almost totally eliminated the release of CPK and LDH from the muscle. unknown
2262148 The cardiomyocytes' damages were proved by higher levels of creatine phosphokinase and lactate dehydrogenase in the blood of heat treatment shop workers. Human
Rats
2096995 Serum levels of total sialic acid, carcinoembryonic antigen (CEA), ferritin, lactate dehydrogenase, and creatine phosphokinase were measured both in tumor drainage blood (axillary vein) and in peripheral blood obtained from 121 breast cancer patients during surgery. unknown
1870318 During exercise tests the following serum parameters were measured: lactate, pyruvate, glucose, triglycerides, nonesterified fatty acids, lactate dehydrogenase, alpha-hydroxybutyrate dehydrogenase, malate dehydrogenase, creatine phosphokinase. Human
1956272 During recovery, muscle enzymes continued to rise and peaked (creatine phosphokinase on the day following the triathlon at 4920 +/- 685 U.ml-1; range 1321-16,746); creatine phosphokinase and lactate dehydrogenase remained significantly elevated at the end of the recovery period. Human
1754299 It should be underscored that transient abnormalities in routine blood tests (glutamic oxaloacetic transaminase, lactate dehydrogenase, and creatine phosphokinase) were present soon after birth, despite his asymptomatic clinical course. unknown
1664782 The activity of lactic dehydrogenase was significantly increased by the stress, and the activities of creatine phosphokinase and alkaline phosphatase were also increased slightly. Ducks
1842714 Serum creatine phosphokinase, lactic dehydrogenase, estradiol, progesterone and testosterone levels in male patients with acute myocardial infarction and unstable angina pectoris. Human
1842714 In order to study predisposing effects of sex hormones in acute myocardial infarction and in unstable angina pectoris, serum estradiol, progesterone, testosterone, creatine phosphokinase (CPK), and lactic dehydrogenase (LDH) levels were measured in 26 male patients with acute myocardial infarction, and in 14 male patients with unstable angina pectoris, and in 15 healthy male patients as a control. unknown
1842714 There was a positively good correlation between the serum CPK and LDH levels in acute myocardial infarction and the serum estradiol levels r = 0.66; 0.70; p < 0.05). unknown
1609445 Serum was separated and collected for determination of glucose, blood urea nitrogen (BUN), creatinine, uric acid (UA), total proteins, cholesterol, sodium, potassium, calcium, inorganic phosphorus, alkaline phosphatase, aspartate aminotransferase (AST, GOT), alanine aminotransferase (ALT, GPT), lactate dehydrogenase and creatine phosphokinase (CPK). Rats
1633370 Furthermore, elevated serum creatine phosphokinase and lactate dehydrogenase levels which were thought to be delivered from skeletal muscle returned to the normal range concomitant with the correction of hypocalcemia. Human
1505622 In these rats, the serum levels of low density lipoprotein, free cholesterol, total bilirubin, blood urea nitrogen, and triglyceride and the activities of glutamic oxalacetic transaminase, glutamic pyruvic transaminase, creatine phosphokinase, alkaline phosphatase, and lactate dehydrogenase increased markedly and the level of high density lipoprotein, the oxygen partial pressure, and the cholinesterase activity decreased. Rats
1405577 This was shown by the elevations in creatine phosphokinase levels in the competitive cyclists with the marathoners having higher than the normal ranges for lactate dehydrogenase and lower than normal ranges for hematocrit and red blood cells. Human
1405577 Significant differences for albumin, cholesterol, creatine phosphokinase, globulin, hematocrit, lactate dehydrogenase, low density lipoprotein, total protein, red blood cells and triglycerides were observed between the groups. unknown
1413484 Blood samples for measuring arterial and venous pH and blood gases, haemoglobin, glucose and lactic acid concentrations and the serum activity of the enzymes creatine phosphokinase (CK), lactate dehydrogenase, aspartate aminotransferase and alkaline phosphatase were taken before exercise and immediately after each journey (morning and afternoon) of the daily work. Horses
1321636 Decreases in neutral-red uptake by thyroid cells and in intracellular lactate dehydrogenase, alpha-hydroxybutyryldehydrogenase and creatine phosphokinase activities were induced by 30 and 75 microM cisplatin. unknown
1300023 After a 5 min of calcium-free perfusion [standard Krebs-Henseleit (K-H) buffer without calcium, gassed with 95% O2 and 5% CO2] followed by a 20 min of normal K-H buffer (Ca2+ 2.5 mmol/L) perfusion, extensive and rapid myocardial injury was observed: release of massive cellular enzymes such as lactic dehydrogenase (LDH) and creatine phosphokinase (CPK), significant decrease of myocardial anti-oxygen free radical enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities but no obvious change of myocardial lipid peroxides such as malondialdehyde (MDA) content was observed. unknown
2080517 Type A also caused a significant increase in the plasma levels of K+, lactate dehydrogenase, creatine phosphokinase, inorganic phosphate and glucose. unknown
1885405 1, addition of .1 or 1% Trp to corn-soybean meal diets had no effect on growth performance or leukocyte and relative eosinophil counts or on plasma aspartate transferase, creatine phosphokinase, and lactate dehydrogenase activities. Swine
1669023 Myocardial metabolism under such conditions as assessed by examination of coronary effluent concentrations of lactic acid (LA), lactic acid dehydrogenase (LDH) and creatine phosphokinase (CPK) was rapidly and severely compromised. unknown
1669023 For example, LA, LDH and CPK all went from elevated values towards normal levels. unknown
1618087 The enzymes are aldolase (ALD), pyruvate kinase (PYK), phospho hexo-isomerase (PHI), lactic dehydrogenase (LDH), creatine phosphokinase (CPK), hydroxybutyrate dehydrogenase (HBD), glutamic-pyruvic transaminase (GPT), alkaline phosphatase (AKP), acid phosphatase (ACP), r-glutamyl-transpeptidase (gamma-GT). Human
9259812 Venous blood was sampled before and immediately after the show jumping and was analysed for packed cell volume, LA, blood glucose (GLU), total plasma protein, bicarbonate, sodium, potassium (K+), chloride, calcium and activities of plasma lactate dehydrogenase, creatine phosphokinase (CK) aspartate amino transferase and gamma glutamyl transferase (GGT). Horses
8459879 Muscle enzymes, creatine phosphokinase, lactic dehydrogenase and serum glutamic oxaloacetic transaminase were all significantly raised indicating rhabdomyolysis. Human
8351544 Total lactate dehydrogenase (LDH) values were elevated in 115 patients (78%); total creatine phosphokinase (CPK) values were elevated in 100 (68%). Human
8351544 Nineteen patients (25%) with abnormal rhythms had elevated LDH values, and 26 (35%) had elevated CPK values. unknown
8441741 Both agents reduced the force of contraction and increased the release of glutathione, oxidized glutathione, lactate dehydrogenase and creatine phosphokinase into the perfusion fluid. Rats
8462644 Plasma biochemical values, blood urea nitrogen (BUN), glucose, aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and creatine phosphokinase (CPK), were compared between the samples collected from orbital sinus, heart and tail vein in mice, rats and hamsters. Hamsters
Mice
Rats
8462644 The significant higher values of AST, LDH and CPK were shown in samples from orbital sinus as compared with that from other sites. unknown
8262151 Interestingly, the induction of muscle creatine phosphokinase (MCK) activity was sensitive to BFA, although a constitutive expression of lactate dehydrogenase, one of the cytosolic housekeeping enzymes, was resistant to BFA. Mice
8292692 Serum levels of lactate dehydrogenase (LDH), glutamic oxaloacetic transaminase (GOT), aldolase, and alkaline phosphatase (AP) were compared to serum CPK levels in each patient group. Human
8292692 However, correlations were much higher in the NMS group, and regression lines for CPK-LDH and CPK-GOT pairs differed significantly between patient groups. unknown
5711011 Serum and cerebrospinal fluid creatine phosphokinase, aldolase and lactic dehydrogenase in cerebrovascular diseases. Human
5763910 Serum and cerebrospinal fluid enzymes in cerebrovascular disease. Creatine phosphokinase, aldolase, and lactic dehydrogenase. Human
4726270 Study of creatine phosphokinase, lactic dehydrogenase and transaminases in neuromuscular diseases. Human
5643462 Lactate dehydrogenase isoenzymes, glutamate dehydrogenase, glutamate-alanyl aminotransferase and creatine phosphokinase in the peripheral blood of brain-damaged rats. Rats
5709968 Lactic acid dehydrogenase (LDH) and creatine phosphokinase (CPK) isozymes in muscle from neuromuscular diseases. Human
8280783 Ferrylmyoglobin formation was found to be formed considerably before intracellular release of either creatine phosphokinase or lactic dehydrogenase. unknown
8169849 Abnormal chemistries, including a large increase of the activity of serum lactate dehydrogenase and creatine phosphokinase, an index of the myocardial damage caused by doxorubicin, were also observed. unknown
8169849 Pretreatment of rats with 25 I.U./kg b.wt. of vitamin A, once a day for 2 days, before injecting doxorubicin, substantially reduced the peroxidative damage to heart lipids and proteins, and markedly lowered the serum values of lactate dehydrogenase and creatine phosphokinase to values close to those of control rats. unknown
7974879 Significant increases in glutamic oxaloacetic transaminase, alkaline phosphatase, creatine phosphokinase and lactate dehydrogenase concentrations in the nutrient medium were observed at over 400 shock doses, reflecting damage to the cell membrane. unknown
7981542 After hypothermic incubation, creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) were measured, and the myocytes were then cultured for 24 h at 37 degrees C to evaluate the recovery of the myocyte beating rate. unknown
7981542 Moreover, the release of CPK and LDH was significantly suppressed in group 12 compared to the control, being 57.7 +/- 27.6 mIU/flask (P < 0.05) and 275.1 +/- 83.0 mIU/flask (P < 0.025), respectively, in group I2, and 96.8 +/- 38.3 mIU/flask and 439.6 +/- 147.1 mIU/flask in group I0. unknown
7814302 Serum glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, lactic dehydrogenase, and creatine phosphokinase levels were measured before and 1 day after the procedure in 14 patients who underwent MCE and coronary arteriography, and in a group of 14 patients who underwent coronary arteriography alone. Human
7840721 Creatine phosphokinase and lactic dehydrogenase significantly correlated with severity injury index, but not MB fraction. Human
7945601 Levels of brain creatine phosphokinase (CPK), glutamic oxalic transaminase, lactate dehydrogenase, and lactate in lumbar cerebrospinal fluid (CSF) were analyzed as an adjunctive study in a randomized clinical trial evaluating the effects of thiopental loading intravenously in comatose survivors of cardiac arrest. Human
7784818 Typical laboratory markers were: CD4 cell counts below 100 x 10(6)/l in 16 cases, elevation of serum lactic dehydrogenase in 16 and creatine phosphokinase (in 4/6), normal or only slightly elevated C-reactive protein (in 9/11), positive Toxoplasma gondii IgG antibodies in 15/16 and negative IgM antibodies in all 16. Human
7792954 Over the next 5 days, he developed a fulminant septicemia-like illness with progressive hypotension, disseminated intravascular coagulation, and very high serum lactic acid dehydrogenase (2,150 U/L) and serum creatine phosphokinase (5,395 U/L) levels, and died. Human
Toxoplasma
7622259 On day 5 of therapy the activity of aspartate aminotransferase (AST), lactic dehydrogenase (LDH), creatine phosphokinase (CPK) and gamma-glutamyl-transpeptidase (gamma GT) in the CSF was determined by photocolorimetric assay and the concentration of creatine kinase BB (CK-BB) by ELISA. unknown
7622259 The activity of AST, CPK, LDH, and gamma GT in the CSF had returned to normal by the 5th day of therapy, but almost a 7-fold higher concentration of CK-BB was registered. unknown
8546365 In the EQAS for clinical chemistry the following analytes are considered: glucose, urea, proteins, albumin, chloride, sodium, potassium, total calcium, inorganic phosphate, iron, urate, creatinine, cholesterol, triglycerides, aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, creatine phosphokinase, gamma glutamyl transferase and alkaline phosphatase. Human
7885029 After hypothermic incubation, creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) were measured. unknown
7885029 The release of CPK and LDH was significantly suppressed with 10(-4) M NRD (10(-4) M: 24.1, 257.2 MIU/flask; control: 125.4, 459.5 mIU/flask, respectively). unknown
7885029 However, 10(-4) M DTZ showed significantly increased CPK and LDH levels compared to the control (10(-4) M: 203.3, 883.4 mIU/flask; control: 112.3, 457.4 mIU/flask, respectively). unknown
7885029 There were no significant differences for CPK and LDH levels among the PGE groups. unknown
8729164 This possibility was confirmed by the clinical course of ECG change, with elevated CPK and lactate dehydrogenase and a slightly elevated antibody titer for echovirus. Human
8921580 We analyzed the effect of ANP on cell number, DNA synthesis, total RNA level, the expression of cell-cycle-specific and sarcomeric proteins, and levels of lactate dehydrogenase and creatine phosphokinase. Chick Embryo
8938287 In 18 patients, lumbar puncture cerebrospinal fluid was analyzed 24 to 48 hours after surgery; the analyses included measurement of lactic dehydrogenase, creatine phosphokinase, adenylate kinase, and neuron-specific enolase. Human
9118156 We have evaluate the hemodynamic changes (coronary and aortic flows, systolic aortic pressure, work minute), reperfusion arrhythmias, heart weight changes (ww/dw), myocardial enzyme release (creatine phosphokinase and lactic dehydrogenase) and microcirculation permeability changes (FITC.albumin diffusion), as an index of endothelial function. Rats
9067316 Plasma creatine phosphokinase, lactic dehydrogenase, glutamic-oxaloacetic transaminase and glutamic-pyruvic transaminase activities significantly increased in rats immersed in 23 degrees C water for 6 hr after restraint (water immersion stress). Rats
9134819 The enzyme levels of myocardial specimens including ALT, AST, LDH, creatine phosphokinase (CK), superoxide dismutase (SOD), and malondialdehyde (MDA) were recorded and compared both between the two groups and within each group. unknown
2325331 Lactate dehydrogenase and creatine phosphokinase isoenzymes in tissues of laboratory animals. Guinea Pigs
Hamsters
Mice
Rats
2325331 The lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) isoenzyme distributions in tissues of the ICR mouse, Wistar rat, guinea pig and golden hamster were analyzed by histoelectrophoresis. unknown
2325331 Histoelectrophoresis was for the direct analysis of LDH and CPK isoenzymes in the tissues and had high practical value compared with previous tissue-extraction methods. unknown
8473790 Arterial blood samplings for Creatine phosphokinase MBisozyme (CPK-MB), alpha-hydroxy lactic acid dehydrogenase (HBDH), thiobarbituric acid reactive substance (TBA) were measured up to 24 hours after the reperfusion. Human
8362483 Serum samples were analysed for cortisol, creatine phosphokinase (CPK) lactate dehydrogenase (LDH) and LDH-isoenzymes. Swine
8362483 Pigs at abattoir Y had higher mean serum levels of CPK than pigs at abattoir X (3.63 log10 U/litre vs 3.41 log10 U/litre, 0.03 sed, P < 0.001), higher total LDH activities (1269.5 U/litre vs 922.8 U/litre, P < 0.001) and higher cortisol concentrations (1.70 log10 ng/ml vs 1.51 log10 ng/ml, P < 0.001). unknown
8253399 Elevated serum levels of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) are generally present in cases of muscle or heart disease, though there are some exceptions. Human
8253399 The neurologic examination was normal, but serum levels of CPK and LDH, and especially isoenzymes of striated muscle, were elevated. unknown
8495702 Muscle enzyme activity (serum glutamine oxaloacetate transaminase, lactate dehydrogenase, creatine phosphokinase), maximal aerobic capacity (VO2max), muscle strength (MS), and rating of subjective sensation of fatigue were assessed prior to and upon conclusion of treatment. unknown
968173 The efflux of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) which issued from each organ was determined over a 5 hour period. Mice
975615 Under anaerobic conditions there was an increase in the release of malate dehydrogenase, lactate dehydrogenase and creatine phosphokinase from isolated perfused guinea-pig hearts. Guinea Pigs
8069260 Thirty min of reperfusion following 30 min of global ischemia produced contractile failure and the marked release of lactate dehydrogenase (LDH) and creatine phosphokinase (CPK). Rats
8069260 The depressed contractile function after the ischemia was improved, and the increased releases of LDH and CPK were significantly ameliorated by benidipine. unknown
8067023 Lactate dehydrogenase level was increased in patients who had been working at the farm for 1-5 and 11-15 years while activities of hydroxybutyrate dehydrogenase and creatine phosphokinase were found to be raised in patients with 11-15 and 16-20-year history of service respectively. unknown
7945601 Levels of brain creatine phosphokinase (CPK), glutamic oxalic transaminase, lactate dehydrogenase, and lactate in lumbar cerebrospinal fluid (CSF) were analyzed as an adjunctive study in a randomized clinical trial evaluating the effects of thiopental loading intravenously in comatose survivors of cardiac arrest. Human
7942027 Increased muscle enzymes including creatine phosphokinase (CPK) or lactic dehydrogenase (LDH) were all positive in nine patients. Human
7753452 Creatine phosphokinase in groups I, II and III were 985-7516 (1358 +/- 368), 917-5277 (1431 +/- 188), and 517-816 (772 +/- 69) and lactic dehydrogenase levels were 757-3727 (2191 +/- 56), 592-3454 (1923 +/- 164), and 446-958 (632 +/- 115) respectively. Human
7784818 Typical laboratory markers were: CD4 cell counts below 100 x 10(6)/l in 16 cases, elevation of serum lactic dehydrogenase in 16 and creatine phosphokinase (in 4/6), normal or only slightly elevated C-reactive protein (in 9/11), positive Toxoplasma gondii IgG antibodies in 15/16 and negative IgM antibodies in all 16. Human
7792954 Over the next 5 days, he developed a fulminant septicemia-like illness with progressive hypotension, disseminated intravascular coagulation, and very high serum lactic acid dehydrogenase (2,150 U/L) and serum creatine phosphokinase (5,395 U/L) levels, and died. Human
Toxoplasma
7622259 On day 5 of therapy the activity of aspartate aminotransferase (AST), lactic dehydrogenase (LDH), creatine phosphokinase (CPK) and gamma-glutamyl-transpeptidase (gamma GT) in the CSF was determined by photocolorimetric assay and the concentration of creatine kinase BB (CK-BB) by ELISA. unknown
7622259 The activity of AST, CPK, LDH, and gamma GT in the CSF had returned to normal by the 5th day of therapy, but almost a 7-fold higher concentration of CK-BB was registered. unknown
7640455 The levels of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) in the solutions were measured after each hypothermic incubation, following which the myocytes were cultured for an additional 24 h at 37 degrees C to evaluate the recovery of the myocyte beating rate. unknown
7640455 The release of CPK and LDH in the LR, UW, and NS groups was significantly suppressed compared to the ST and GK groups, with the greatest suppression observed in the LR group. unknown
7640455 Moreover, the ST and GK groups had the highest CPK and LDH levels, respectively. unknown
7653617 Ischemia-induced cardiac dysfunction, including increases in left ventricular end-diastolic pressure and lactate dehydrogenase and creatine phosphokinase release at reperfusion, was attenuated by TTX and R-56865 (0.1-320 nM). Guinea Pigs
8546365 In the EQAS for clinical chemistry the following analytes are considered: glucose, urea, proteins, albumin, chloride, sodium, potassium, total calcium, inorganic phosphate, iron, urate, creatinine, cholesterol, triglycerides, aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, creatine phosphokinase, gamma glutamyl transferase and alkaline phosphatase. Human
8595614 Recovery of mechanical function and lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) activities in the coronary effluent were recorded throughout 90 min reperfusion. Rabbits
8595614 Furthermore, CPK and, to a lesser extent, LDH release during reperfusion was attenuated in hearts from CFR compared to controls. unknown
8682355 The clinical picture included fever, weakness, arthralgia, pedal edema, mild bilateral pleural effusions, anemia, leukocytosis, azotemia with a maximum of 330 mg/dl of urea, creatine to a maximum of 9.8 mg/dl, hypoproteinemia, severe metabolic acidosis, marked increase in lactate dehydrogenase (LDH) and creatine phosphokinase (CPK), microscopic hematuria, sterile leukocyturia, normoglycemic glucosuria and phosphaturia with diminished tubular reabsorption of phosphorus. Human
7885029 After hypothermic incubation, creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) were measured. unknown
7885029 The release of CPK and LDH was significantly suppressed with 10(-4) M NRD (10(-4) M: 24.1, 257.2 MIU/flask; control: 125.4, 459.5 mIU/flask, respectively). unknown
7885029 However, 10(-4) M DTZ showed significantly increased CPK and LDH levels compared to the control (10(-4) M: 203.3, 883.4 mIU/flask; control: 112.3, 457.4 mIU/flask, respectively). unknown
7885029 There were no significant differences for CPK and LDH levels among the PGE groups. unknown
8641713 Further, the biochemical studies, estimation of enzymes plasma creatine phosphokinase and lactate dehydrogenase, confirmed the safety profile of NVCR. Mice
Rats
8729164 This possibility was confirmed by the clinical course of ECG change, with elevated CPK and lactate dehydrogenase and a slightly elevated antibody titer for echovirus. Human
8921580 We analyzed the effect of ANP on cell number, DNA synthesis, total RNA level, the expression of cell-cycle-specific and sarcomeric proteins, and levels of lactate dehydrogenase and creatine phosphokinase. Chick Embryo
8824468 The following parameters were measured: stroke work index, coronary flow and arteriovenous oxygen consumption, 6-keto prostaglandin F1alpha and prostaglandin E2 as markers of endothelial cell activation; creatine phosphokinase and lactate dehydrogenase for evaluation of the extent of myocardial damage; TNFalpha and IL-6 as markers of mononuclear cell activation. Human
Swine
8824468 Myocardial damage was minimal in transgenic hearts, whereas normal pig hearts produced a threefold increase of creatine phosphokinase and lactate dehydrogenase levels. unknown
8772459 Succinate dehydrogenase, citrate synthase, lactate dehydrogenase, and creatine phosphokinase continued to change up to 12 wk of stimulation. unknown
8967955 In addition the lactate dehydrogenase, gamma-glutamyl transpepetidase, alkaline phosphatase and creatine phosphokinase activities have been quantitated in various human Sertoli cell preparations. unknown
9127798 Creatine phosphokinase, lactic dehydrogenase, aspartate transaminase and alanine transaminase venous blood levels were significantly decreased after diltiazem injection compared with the SMA ligation group. Rats
9812719 After reperfusion, the blood sample and myocardium were taken to assay plasma creatine phosphokinase (CPK), lactate dehydrogenase (LDH), and cations in myocardium. unknown
9812719 RESULTS: Hyp 10 mg.kg-1 i.v. depressed changes in LVP, LV +/- dp/dtmax, ECG, plasma CPK, LDH, and cations (Ca2+, Mg2+, Na+) in myocardium induced by ischemia/reperfusion in rabbits. unknown
8938287 In 18 patients, lumbar puncture cerebrospinal fluid was analyzed 24 to 48 hours after surgery; the analyses included measurement of lactic dehydrogenase, creatine phosphokinase, adenylate kinase, and neuron-specific enolase. Human
9118156 We have evaluate the hemodynamic changes (coronary and aortic flows, systolic aortic pressure, work minute), reperfusion arrhythmias, heart weight changes (ww/dw), myocardial enzyme release (creatine phosphokinase and lactic dehydrogenase) and microcirculation permeability changes (FITC.albumin diffusion), as an index of endothelial function. Rats
9135354 Serum creatine phosphokinase (CK), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and lactate dehydrogenase (LDH) concentrations were measured before, and at 30 min and 20 h after induction of anaesthesia. Human
9143785 Rats in the N and NH groups had significantly increased serum creatine phosphokinase, lactate dehydrogenase, glutamic oxaloacetic transaminase and serum total cholesterol levels compared with rats in the C group. unknown
9186889 Biochemical assay of serum creatine phosphokinase (CK) and lactate dehydrogenase (LDH) showed marked elevations [7166 +/- 2064 IU and 1626 +/- 211 Berger-Broida U/ml (B-B U/ml)] six hours after injection, indicative of rhabdomyolysis. Mice
9067316 Plasma creatine phosphokinase, lactic dehydrogenase, glutamic-oxaloacetic transaminase and glutamic-pyruvic transaminase activities significantly increased in rats immersed in 23 degrees C water for 6 hr after restraint (water immersion stress). Rats
9134819 The enzyme levels of myocardial specimens including ALT, AST, LDH, creatine phosphokinase (CK), superoxide dismutase (SOD), and malondialdehyde (MDA) were recorded and compared both between the two groups and within each group. unknown
8005703 Simultaneous measurement of sperm LDH, LDH-X, CPK activities and ATP content in normospermic and oligozoospermic men. Human
8005703 Total lactate dehydrogenase (LDH), LDH-X, creatine phosphokinase (CPK) activities and ATP content were measured in washed spermatozoa from 188 normospermic and 94 oligozoospermic men. unknown
8005703 In oligozoospermic men the activity of sperm LDH and LDH-X was related significantly to sperm CPK activity (r = 0.5486 and r = 0.4442, respectively), whereas this relationship was less evident in normospermic men (r = 0.4124 and r = 0.3844, respectively). unknown
8005703 Sperm ATP content was related weakly to sperm LDH, LDH-X and CPK activities both in oligozoospermic and normospermic men. unknown
8005703 After separation on a discontinuous (40% and 80%) Percoll gradient LDH, LDH-X, CPK activities and ATP content in 80% separated sperm fractions from 48 normospermic and 30 oligozoospermic men were found to be significantly lower than in the initial semen sample in both groups of subjects. unknown
8005703 The 80% separated sperm fractions from oligozoospermic and normospermic men did not differ in their LDH or LDH-X activities or ATP content, whereas sperm CPK activity was still significantly higher in oligozoospermic men. unknown
7841727 Enzymatic determinations in cerebrospinal fluid (CSF) of aspartate aminotransferase (AST), lactic dehydrogenase (LDH), gammaglutamyl transpeptidase (GGT), creatine phosphokinase (CPK) and creatine kinase BB (CK-BB) were performed in 16 patients with aseptic meningitis (AM), in 25 children with bacterial meningitis (BM) and in 15 patients with meningism. Human
7863489 Creatine Phosphokinase (CPK), Creatine Phosphokinase isozyme (CPK-MB) and Lactic Dehydrogenase (LDH) in group B (n = 45, receiving ascorbic acid) were lower (p < 0.05) than in group A (n = 40, no ascorbic acid) during and after CPB. Human
7648496 The activity of lactate dehydrogenase isoenzyme (LDH) and creatine phosphokinase isoenzyme (CPK-MB) were increased in the latter group. unknown
8607339 The diagnosis of the latter is based upon serum elevatIon of certain enzymes, such as aspartate amino transferase, lactate dehydrogenase and creatine phosphokinase. Human
8607339 OBJECTIVE: To determine serum creatine phosphokinase, lactate dehydrogenase and aspartate amino transferase levels in late pregnancy, and throughout labor and early puerperium. unknown
8607339 METHODS: Fifty women having normal pregnancies followed by uneventful vaginal deliveries were prospectively studied for serum lactate dehydrogenase, aspartate amino transferase and creatine phosphokinase including its MB isoenzyme before, during and after labor. unknown
8634377 The literature covering the following biochemical markers is reviewed: adenylkinase, creatine phosphokinase isoenzyme BB (CK-BB), lactate, neuron-specific enolase (NSE), S-100 protein, myelin basic protein, lactate dehydrogenase, aspartate aminotransferase, glutathione, vasointestinal neuropeptide, and 7B2-specific neuropeptide. Human
8888948 Lactic acid, lactic acid dehydrogenase, and creatine phosphokinase levels in the perfusate tended to be elevated progressively with increasing duration of EtOH perfusion and pH tended to be reduced (p < 0.05). unknown
8959529 The serum concentrations of the following were determined: calcium, magnesium, zinc, aluminium, inorganic phosphorus, cholesterol, glutamate-oxaloacetate transaminase, glutamate-pyruvate transaminase, lactate dehydrogenase, cholinesterase, creatine phosphokinase, blood urea nitrogen and N-terminal parathyroid hormone. unknown
9257258 From the coronary sinus effluent, samples were taken for the determination of 6-keto prostaglandin F1 alpha, prostaglandin E2, creatine phosphokinase, and lactate dehydrogenase, respectively. Human
Macaca mulatta
Swine
9257258 As markers of myocardial damage, creatine phosphokinase and lactate dehydrogenase increased in all groups. unknown
9368909 Maximum contractility, +dF/dtmax, -dF/dtmax, heart rate, contractility rate product, coronary flow and lactate dehydrogenase, creatine phosphokinase enzyme leakage were measured in all groups during pre-ischemic and post-ischemic periods (10 min after reperfusion). Rats
9416902 Cardiomyocytes were subjected to simulated ischemic stress, and survival was estimated through assessment of lactate dehydrogenase and creatine phosphokinase release. Adenoviridae
Rats
9362034 At the later fattening stage (5 to 20 months after introduction), statistically significant increases were observed in the mean serum activities of lactic dehydrogenase, glutamic-oxalacetic transaminase, gamma-glutamyl transpeptidase, and creatine phosphokinase, the mean serum contents of triglyceride, total cholesterol, albumin (Alb), total protein, blood urea nitrogen, magnesium, and vitamin E, and the mean serum calcium (Ca)/inorganic phosphorus (IP) ratio, and statistically significant decreases were seen in the mean serum alkaline phosphatase activity and the mean serum contents of glucose, IP, and vitamin A. Cattle
9455518 These were associated with significant elevations of creatine phosphokinase and lactate dehydrogenase levels. Human
Mice
9527408 Anesthetic effects on extrarenal injury (plasma creatine phosphokinase, lactate dehydrogenase, and hematocrit levels), acute intrarenal heme loading (cast formation), and BP during the initiation phase of renal injury (0 to 4 h after glycerol injection) were also assessed. unknown
9570342 Serum biochemical parameters (sodium, potassium, chloride, calcium, magnesium, phosphorus, amylase, creatine phosphokinase, and lactate dehydrogenase) were measured after 28 days of exposure and serum cortisol after 90 and 190 days. Mice
9568324 The levels of marker enzymes for liver function, namely transaminases (SGPT, SGOT), creatine phosphokinase (CPK), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH) were estimated in the sera of burn patients by administering trypsin: chymotrypsin preparation and comparing with an untreated group. Human
9671889 Serum creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) were measured to examine the value of muscle injury in predicting incontinence. c-Fos immunostaining in the spinal cord was used as a marker of nerve injury. Rats
9671889 The serum CPK and LDH levels were markedly elevated, but no difference was noted between the continent and incontinent rats. unknown
9212666 Acute renal failure developed because of hypoperfusion of the kidney caused by acute circulatory failure and the tumor lysis syndrome, and rapid increases in the concentrations of lactate dehydrogenase, creatine phosphokinase, and uric acid in serum after the tumor collapsed. unknown
9725521 Interleukin 6 and 8, as well as serum albumin, creatine phosphokinase, lactate dehydrogenase and creatine phosphokinase-MB fractions were also analyzed. unknown
9766526 The analytical parameters included cell number, DNA content, expression of cell cycle-specific and cardiomyocyte-specific proteins, and creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) enzyme activities. unknown
9766526 The level of LDH was elevated (P < 0.01), but that of CPK was lowered in LCa. unknown
9689585 The recovery of spontaneous contraction rate and enzyme leakage (creatine phosphokinase and lactate dehydrogenase) during both ischemia and reoxygenation correlated with the degree of inhibition of intracellular Ca2+ accumulation. unknown
9804569 There were significant increases in clinical scores and creatine phosphokinase, lactate dehydrogenase, and muscle histopathology scores in BALB/c mice compared with those in DBA/2N mice and sham-surgery mice. Mice
9804569 Muscle histopathology scores of the cranial tibialis and quadriceps correlated well with clinical signs, creatine phosphokinase, and lactate dehydrogenase, and indicated the greatest pathology in these muscle groups. unknown
9928632 A single dose of adriamycin (10 mg/kg body weight) caused myocardial damage that was manifested by elevation of serum enzymes, glutamate-oxaloacetate transaminase (GOT), glutamate-pyruvate transaminase (GPT), lactate dehydrogenase isoenzyme (LDH-iso) and creatine phosphokinase isoenzyme (CPK2-MB). unknown
9840728 CR enhanced DOX-induced increase in plasma lactate dehydrogenase, creatine phosphokinase (CPK) and CPK-MB isozyme activities, as well as the cardiac malondialdehyde level. unknown
9950523 The authors have tested as "metabolic" markers the enzymes lactate dehydrogenase and creatine phosphokinase. Human
9888261 All hearts were compared for their preischemic and postischemic contractility, heart rate, contractility rate product, coronary flow, lactate dehydrogenase, creatine phosphokinase enzyme leakage and wet/dry weight ratio. Rats
9888261 All groups had similar contractility (for control, HES, gelatin and dextran groups the values at minute 10 of reperfusion were 59+/-9, 56+/-11%, 61+/-14%, 49+/-14% of initial values [P>0.05, respectively]) and enzyme leakage (lactate dehydrogenase 4.1+/-1.0, 8.1+/-1.5, 5.8+/-1.4, 3.7+/-1.2 [P>0.05] and for creatine phosphokinase 3.9+/-2.5, 6.4+/-3.7, 5.5+/-1.3, 5.5+/-0.8, P>0.05] IU xmin(-1) x g dry tissue(-1) in the reperfusion period, respectively) results as compared with the control group. unknown
10023749 Serum activities of lactate dehydrogenase (LDH), glutamic oxaloacetic transaminase (GOT), and creatine phosphokinase (CPK), and serum levels of Na+ and K+ were measured in blood samples from healthy broilers and from broilers suffering from Sudden Death Syndrome (SDS) within 30 min after death. Chickens
10023749 The LDH, GOT, and CPK activities and Na+ level were unchanged for the post-mortem period of 30 min, but the K+ level increased. unknown
10322879 RESULTS: MXLDP pretreatment (30 and 120 mg.kg-1.d-1) prevented significantly reduction of myocardial superoxide dismutase (SOD) activity, reduced malondialdehyde (MDA) content and myocardial creatine phosphokinase (CPK) release; diminished significantly myocardial infarction size, decreased lactate dehydrogenase (LDH) activity and increased the concentration of serum NO in comparison with the control (P < 0.05-0.01). unknown
10232775 In addition, a decrease in plasma enzymes - alkaline phosphatase (ALP), glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT), creatine phosphokinase (CPK), gamma glutamyl transpeptidase (GGT) and lactate dehydrogenase (LDH) was noted. unknown
10547077 After anoxic perfusion, release of lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) as well as MYO were all markedly and significantly increased from ethanol-exposed hearts compared with those from control rats. unknown
10547077 Comparisons with absolute values from the previous experiments suggest that nitrendipine increased release of LDH and CPK from control hearts with little effect on these indices from ethanol-exposed hearts. unknown
10527512 A new analytical approach has been applied to the determination and characterization of mercury-accessible -SH groups in pure native protein samples (ovalbumin, hemoglobin, glyceraldehyde-3-phosphate dehydrogenase, aldolase, pyruvate kinase, hexokinase, lactate dehydrogenase, alcohol dehydrogenase, creatine phosphokinase, lysozyme, and cytochrome c). Human
10598118 Compared with controls, hearts from ethanol-exposed rats were significantly protected against myocardial damage, as shown by a marked reduction in release of intracellular proteins (lactate dehydrogenase, creatine phosphokinase, and myoglobin) during the reperfusion phase. unknown
10665798 An increase in the level of serum enzymes, such as aspartate transaminase, alkaline phosphatase, creatine phosphokinase, lactate dehydrogenase after D. russelli venom injection in albino rats is indicative of cell or tissue damage. unknown
10683355 METHODS AND RESULTS: At 30 minutes of reperfusion after 30-minute global ischemia, the percent recovery of left ventricular developed pressure was improved, and the creatine phosphokinase and lactate dehydrogenase leakage was reduced in a concentration-dependent manner when JTV519 was administered in the coronary perfusate both at 5 minutes before the induction of ischemia and at the time of reperfusion. Rats
10675279 This protection was evidenced from the significant reduction in serum enzymes: lactate dehydrogenase elevated level, 24 h and creatine phosphokinase elevated levels, 24 h and 48 h after doxorubicin administration. unknown
10752789 Moreover, the elevated preoperative serum levels of muscle-associated enzymes, including aspartate transaminase, creatine phosphokinase, lactate dehydrogenase, and aldolase, decreased from 38 to 16 (IU/1), 138 to 42 (IU/1), 672 to 515 (IU/1), and 32.2 to 4.3 (IU/1), respectively. Human
10752197 An additional objective was to determine whether adenosine modifies the release of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH), in the "stunned myocardium". Rabbits
10752197 The administration of adenosine did not diminish the CPK and LDH release significantly when it was given before the ischemia period or the beginning of reperfusion. unknown
10778554 Creatine phosphokinase and lactic dehydrogenase was elevated in 22 (91.6%) and 12 (50%) cases respectively. unknown
10846629 Elevated serum lactate dehydrogenase (LDH), creatine phosphokinase (CPK) and glutamate oxaloacetate transaminase (GOT) activity was observed after isoproterenol treatment. unknown
9310042 The EPC-K1-treated group showed a statistically significant amelioration in the reduction of the isometric muscle contraction, inhibition of the elevation of the muscle wet- to dry-weight ratio, limitation of the muscle level of thiobarbituric acid reactive substances and the serum levels of creatine phosphokinase, lactate dehydrogenase and mitochondrial glutamic oxaloacetic transaminase, and reduction of the extent of muscle injury according to the histological findings. unknown
9678264 A single dose of adriamycin (15 mg/kg) caused myocardial toxicity after 24 h manifested biochemically by elevation of serum enzymes:- Aspartate transaminase (AST, EC: 2.6.1.1), lactate dehydrogenase (LDH, EC: 1.1.1.27), creatine phosphokinase (CPK, EC: 2.7.3.2) and the cardiac iso-enzymes of LDH and CPK. unknown
9810342 Diagnosis of acute myocardial infarction is made with the aid of biomarkers such as structural myocardial proteins, myoglobin (MG) or specific enzymes, creatine phosphokinase isoenzyme MB (CK-MB) or non specific enzymes, lactic dehydrogenase (DHL) and aspartate aminotransferase (AST). Human
9787774 We also measured creatine phosphokinase and serum lactate dehydrogenase isoenzyme activities whose modification may be indicative of muscle fiber damage. unknown
9310042 The EPC-K1-treated group showed a statistically significant amelioration in the reduction of the isometric muscle contraction, inhibition of the elevation of the muscle wet- to dry-weight ratio, limitation of the muscle level of thiobarbituric acid reactive substances and the serum levels of creatine phosphokinase, lactate dehydrogenase and mitochondrial glutamic oxaloacetic transaminase, and reduction of the extent of muscle injury according to the histological findings. unknown
9678264 A single dose of adriamycin (15 mg/kg) caused myocardial toxicity after 24 h manifested biochemically by elevation of serum enzymes:- Aspartate transaminase (AST, EC: 2.6.1.1), lactate dehydrogenase (LDH, EC: 1.1.1.27), creatine phosphokinase (CPK, EC: 2.7.3.2) and the cardiac iso-enzymes of LDH and CPK. unknown
9810342 Diagnosis of acute myocardial infarction is made with the aid of biomarkers such as structural myocardial proteins, myoglobin (MG) or specific enzymes, creatine phosphokinase isoenzyme MB (CK-MB) or non specific enzymes, lactic dehydrogenase (DHL) and aspartate aminotransferase (AST). Human
9787774 We also measured creatine phosphokinase and serum lactate dehydrogenase isoenzyme activities whose modification may be indicative of muscle fiber damage. unknown
9619011 Serum enzymes, including alanine transaminase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and its isoenzymes and creatine phosphokinase (CK) and its isoenzyme, were determined. Human
10846629 Elevated serum lactate dehydrogenase (LDH), creatine phosphokinase (CPK) and glutamate oxaloacetate transaminase (GOT) activity was observed after isoproterenol treatment. unknown
10887983 Increased activities of creatine phosphokinase and lactate dehydrogenase were recorded in only some of the dogs in groups B and C, but there were no significant differences between the mean activities in the three groups. Unknown
10879918 Anemia, leukocytosis, and increased levels of enzymes lactate dehydrogenase, aspartate aminotransferase, creatine phosphokinase, and total serum proteins were found. Unknown
10941728 Mean values for alanine aminotransferase, aspartate aminotransferase, creatine phosphokinase, and lactate dehydrogenase activities as well as blood urea nitrogen, glucose, and sodium concentrations were higher than the upper limit of the reference range for domestic cats. Unknown
11007567 Creatine phosphokinase and lactate dehydrogenase (LDH) activities were measured before and after a prolonged run to assess muscle damage. Unknown
11007567 In conclusion, supplementation with 3.0 g of HMB results in a decreased creatine phosphokinase and LDH response after a prolonged run. unknown
11048664 The salbutamol-induced muscle hypertrophy was associated with an early increase in creatine phosphokinase (CK) and its myocardial isozyme (CKmb), without significant changes in lactate dehydrogenase (LDH), alanine aminotransferase (AAT) and aspartate aminotransferase (DAT). Unknown
11044258 Treatment of the cardiac allografts with PTIO showed most remarkable improvement of the cardiac injury as revealed by significant reduction in aspartate transaminase, lactate dehydrogenase, and creatine phosphokinase concentrations in the perfusate. unknown
11064274 Myocardial injury was assessed by determining the increased release of creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) into the plasma, and by morphometric analysis of the lesion area in heart sections stained with Gomori trichrome. unknown
11064274 RESULTS: ISO induced the release of CPK and LDH by 6 hr and 24 hr, respectively, and produced subendocardial necrosis, which was both acute and resolving following 8 days of ISO. unknown
11064274 DFMO treatment inhibited ISO-induced increases in (i) ODC activity and putrescine and spermidine levels in heart, (ii) CPK and LDH activity in plasma, and (iii) the area of subendocardial lesions. unknown
11056287 Post-mortem examination of blood revealed elevation of creatine phosphokinase-MM (CK-MM) and lactate dehydrogenase-4 and dehydrogenase-5 (LDH-4 and LDH-5). Unknown
11218621 METHODS: In 325 patients, 246 men and 79 women, 61.46 +/- 11.00 and 70.03 +/- 11.30 years mean age respectively, at admission for myocardial infarction and before treatment, we simultaneously measured plasma fibrinogen (FBG), hemochromocytometric parameters and plasma enzyme aspartate and alanine transaminase (AST and ALT), lactate dehydrogenase (LDH) and creatine phosphokinase (CPK). Unknown
11218621 RESULTS: The results showed that FBG was significantly correlated with monocyte (p < 0.001) and LUC (p < 0.05) counts; assumed as dependent variable, further on with FBG, monocyte number was correlated with WBC count, LUC and CPK; further on with monocyte number, WBC with neutrophile and lymphocyte counts, LUC with CPK, CPK with LDH. unknown
11333535 The samples were treated by conventional spectrophotometry to determine enzyme activity as follows: citrate synthase (CS, Krebs cycle), phosphofructokinase (PFK, by common glycolysis), lactate dehydrogenase (LDH, anaerobic glycolysis) and creatine phosphokinase (CPK, use of energy reserves). Unknown
11367646 Serum malonyldialdehyde (MDA), creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) were measured before operation, 30 min after myocardium ischemia, 30 min after reperfusion, 30 min after cardiopulmonary bypass and 24 hours after operation. Unknown
11367646 RESULTS: Serum MDA, CPK and LDH levels in the treated group at both myocardium ischemic period and ischemic reperfusion period were significantly higher than those at before operation (P < 0.05, P < 0.01). unknown
11367646 Comparison between the two groups showed that the serum MDA, CPK and LDH levels were all significantly higher in the control group than those in the control group respectively in all periods (P < 0.01). unknown
11378442 The specific activities of creatine phosphokinase and lactate dehydrogenase of the 6-AN group were the greatest among the three groups, whereas those of the pair-fed group were greater than those of the control group.The results suggest that 6-AN may interfere with the proper maintenance of energy charges and the immune system function. unknown
11419959 Administration of ADR (3 mg kg(-1)i.p., every other day over a period of 2 weeks) resulted in a significant two-fold increase in serum levels of creatine phosphokinase, lactate dehydrogenase and glutamic oxaloacetic transaminase, whereas daily administration of PLC (250 mg kg(-1), i.p. for 2 weeks) induced non-significant change. unknown
11517737 Furthermore, the activities of plasma lactic dehydrogenase, amylase and creatine phosphokinase are ordinarily increased by stress; however these activities in the GSS group decreased to the level in the Control group having no stress. unknown