Medline Repository

Amikacin --> Clindamycin

PMID
Sentence
Species
411610 Tobramycin, amikacin, ampicillin, penicillin G, methicillin, carbenicillin, chloramphenicol, clindamycin, and cephalothin did not interfere with the gentamicin assay. unknown
7440469 Effects of combinations of clindamycin with gentamicin, tobramycin, and amikacin against Staphylococcus aureus. Staphylococcus aureus
7349320 The following minimum inhibitory concentrations (MICs) of antimicrobial agents were determined for greater than or equal to 90% of isolates: methicillin greater than 16 micrograms/ml, clindamycin 1-2 micrograms/ml, tobramycin less than or equal to 1 microgram/ml, cephalothin 8-64 micrograms/ml, kanamycin 2-8 micrograms/ml, amikacin less than or equal to 1-2 micrograms/ml, penicillin 2-greater than or equal to 4 micrograms/ml, ampicillin 2-8 micrograms/ml, trimethoprim-sulfa 4/76-32/608 micrograms/ml tetracycline 1-4 micrograms/ml and chloramphenicol 8-16 micrograms/ml. unknown
7197536 With the checkerboard-technique, it was found in vitro, that methyl-[7-chloro-6,7,8-tridesoxy-6-trans-(1-methyl-4-propyl-L-2-pyrrolidincarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside] (clindamycin) in combination with cefoxitin, cefotaxim, mezlocillin, azlocillin, gentamicin and amikacin has no antagonistic effects against common infective microorganisms such as staphylococci, enterococci and E. coli. Bacteria
7197536 Only 20% of the enterococci strains were inhibited synergistically with the combination clindamycin and gentamicin or with amikacin, respectively. unknown
7197536 In clinical use clindamycin can be administered in combination with cefoxitin, cefotaxime, mezlocillin, gentamicin and amikacin, respectively, without any loss in its activity against the microorganisms tested in this study. unknown
7011222 A randomized comparison of cefoxitin with or without amikacin and clindamycin plus amikacin in surgical sepsis. Human
7011222 Favorable clinical responses were achieved in 34 of 37 patients treated with cefoxitin +/- amikacin, and 29 of 37 patients treated with clindamycin + amikacin; there was no statistical difference between the groups (p greater than 0.1). unknown
6837618 Antibiotic coverage was changed to amikacin, clindamycin, and penicillin G for sepsis and anaerobic cellulitis. unknown
6837618 The serum concentration of amikacin in the presence of penicillin G and clindamycin was overestimated when a multiantimicrobic-resistant Escherichia coli was used as the indicator organism in the microbiological assay. unknown
6551461 The antibacterial agents tested were as follows: ampicillin, sulbenicillin, piperacillin, mezlocillin, cefazolin, cefmetazole, cefoperazone, cefotaxime, ceftizoxime, kanamycin, gentamicin, tobramycin, amikacin, tetracycline, doxycycline, minocycline, nalidixic acid, pipemidic acid, erythromycin and clindamycin. Human
6559664 Six representative clinical isolates of gentamicin- and methicillin-resistant (GRMR) Staphylococcus aureus, constituting phage groups II and III, were susceptible only to amikacin, cefamandole, clindamycin, fosfomycin, fusidic acid, netilmicin, nitrofurantoin, trimethoprim-sulfamethoxazole, and vancomycin (Bauer-Kirby test). Human
Mice
Staphylococcus aureus
6353908 Significant discrepancies were noted for six combinations; cefamandole, cephalothin, neomycin, and nitrofurantoin versus E. coli and amikacin and clindamycin versus S. aureus. unknown
6359913 In an effort to define the optimal preventive antibiotics for gunshot wounds to the abdomen, 100 consecutive patients were randomized while in the emergency department to receive either combination ampicillin, amikacin, and clindamycin, combination doxycycline and penicillin, or carbenicillin (Groups I, II, and III, respectively). Human
6422428 Results show a good correlation between the two methods: more than 90% for carbenicillin, cefazolin, cefoxitin, cefamandole, kanamycin, tobramycin, amikacin, erythromycin, pristinamycin and fusidic acid, between 80 and 90% for penicillin G, ampicillin, oxacillin, gentamicin, doxycycline, chloramphenicol, spiramycin and clindamycin, less than 80% for neomycin, tetracycline, minocycline and oleandomycin. Unknown
6552151 MR S. aureus isolates were also resistant to tetracycline, clindamycin, tobramycin, and amikacin. unknown
3534708 The antibiotics were: penicillin G, amoxycillin, augmentin, oxacillin, streptomycin, kanamycin, tobramycin, dibekacin, amikacin, gentamicin, sisomycin, netilmicin, doxycycline, minocycline, chloramphenicol, erythromycin, josamycin, clindamycin, pristinamycin, rifampin, fusidic acid, fosfomycin, trimethoprim, sulfamethoxazole, cotrimoxazole, and vancomycin. Staphylococcus
2810410 We prospectively studied prophylactic amikacin and clindamycin in 150 abdominal trauma patients requiring laparotomy, analyzing the effects of duration of coverage, dosing interval, and dose. Human
2817651 1 hour preoperatively, 122 patients were administered with the following chemotherapeutic agents: Cefoxitin 2 g i.v.; Cefamandole 2 g i.v.; Ceftriaxone 1 g i.v.; Clindamycin 600 mg i.v.; Amikacin 500 mg i.v.; Gentamycin 160 mg i.v.; Norfloxacin 400 mg by mouth; 30 patients showed obstructive jaundice or obstructed cystic duct. Human
2817651 Mean concentration in the gallbladder bile was: Cefoxitin 209 +/- 86 micrograms/ml; Cefamandole 436 +/- 108 micrograms/ml; Ceftriaxone 482.7 +/- 214.84 micrograms/ml; Clindamycin 64 +/- 22 micrograms/ml; Amikacin 5 +/- 1.4 micrograms/ml; Gentamycin 4 +/- 2 micrograms/ml; Norfloxacin 22 +/- 14 micrograms/ml. unknown
2659296 A comparative analysis of aztreonam + clindamycin versus tobramycin + clindamycin or amikacin + mezlocillin in the treatment of gram-negative lower respiratory tract infections. Gram-Negative Bacteria
Human
2659296 One hundred ten patients were randomized to receive one of the following antibiotic combinations: aztreonam + clindamycin, tobramycin + clindamycin, or amikacin + mezlocillin for the treatment of lower respiratory tract infections (LRTI) caused by gram-negative bacilli. unknown
2631738 The susceptibility of community acquired S. aureus was 90% or higher for dicloxacillin, cephalothin, sulbactam/ampicillin (S/A), clindamycin, rifampicin and amikacin; 85% for cefotaxime and SMX/TMP and only 75% for erythromycin. Human
Staphylococcus aureus
2690432 To verify the role in these patients of a combination therapy of amikacin (300 mg/m2 i.v. every 12 hours) plus ceftazidime (2 g/m2 i.v. every 8 hours) administered as initial empiric treatment, followed in non-responsive cases by a second-line therapy with clindamycin (300 mg/m2 i.v. every 8 hours), we conducted a prospective study in 45 febrile episodes (temperature greater than or equal to 38.5 degrees C) in neutropenic patients (neutrophils less than or equal to 500/ml). Human
2690432 The amikacin-ceftazidime combination followed by clindamycin in non-responsive cases is effective, with moderate toxicity in non-leukemic febrile neutropenic patients. unknown
2701194 Following the introduction of clindamycin, amikacin, ceftriaxone, volume-cycled ventilator and positive end expiratory pressure (PEEP) of 14 cm H2O, stabilization of clinical conditions and gradual recovery were achieved. Human
Legionella
2490476 The pre-incubation of the bacteria with sub-inhibitory concentrations of vancomycin, teicoplanin, amikacin, clindamycin, and roxitromycin did not modify the adherence ability of the microorganisms. Dogs
Staphylococcus
Staphylococcus epidermidis
2490721 The preincubation of 5 strains of Staphylococcus epidermidis with subinhibitory concentrations of vancomycin, clindamycin and amikacin did not influence slime production, whereas ciprofloxacin slightly inhibited it in two strains and oxacillin completely inhibited slime production in the five evaluated strains. Staphylococcus
Staphylococcus epidermidis
3132668 Thirty of 31 patients (96.8%) receiving a combination of cefoxitin with doxycycline and 28 of 31 (90.3%) receiving a combination of clindamycin with amikacin responded to therapy (P = not significant). Chlamydia trachomatis
Human
Neisseria gonorrhoeae
3056240 A total of 113 patients were randomly allocated to receive either ticarcillin plus clavulanic acid (total dose, 20.8 g) or clindamycin (total dose, 2.4 g) plus amikacin (total dose, 1 g) as perioperative antimicrobial prophylaxis for major head and neck surgery. Human
3056240 The wound infection rate was 10% in the group of patients receiving clindamycin plus amikacin and 36% in the group receiving ticarcillin plus clavulanic acid (P less than 0.05). unknown
3869802 Results were compared with those simultaneously obtained for amikacin, netilmicin, tobramycin, norfloxacin, piperacillin, ceftazidime, ceftriaxone and azthreonam against Pseudomonas spp., and for rifampicin, clindamycin, netilmicin and cefoxitin, besides penicillin and methacillin, against Staphylococcus spp. Staphylococcus aureus
3969058 Antibiotics and immunomodulation: effects of cefotaxime, amikacin, mezlocillin, piperacillin and clindamycin. Mice
3969058 In Balb/c mice the effects of cefotaxime, amikacin, mezlocillin, piperacillin and clindamycin were examined. unknown
2228825 Sodium salicylate was combined with the antibiotics amikacin, aztreonam, cefazolin, cefonicid, cefoperazone, ceftizoxime, norfloxacin, doxycycline, clindamycin, imipenem, mezlocillin and trimethoprim-sulphamethoxazole. unknown
2037536 The antimicrobial effect of clindamycin combined with aztreonam or an aminoglycoside (gentamicin, tobramycin or amikacin) was studied against 84 strains of Klebsiella pneumoniae and 18 strains of K. oxytoca with an agar dilution technique. unknown
1945005 The patients were treated with amikacin (7.5 mg/kg/day) and clindamycin. Human
1781473 Ciprofloxacin, amikacin sulfate, aminophylline, clindamycin phosphate, gentamicin sulfate, and tobramycin sulfate were mixed separately in minibags containing 0.9% sodium chloride injection or 5% dextrose injection; admixtures were stored for up to 48 hours at either 4 degrees C or 25 degrees C. unknown
1559013 The effects of 7 days' chemotherapy with penicillin G, piperacillin, mezlocillin, cephalothin, cefamandole, cefotaxime, gentamicin, amikacin, streptomycin, rifampicin, doxycycline, and clindamycin on local tumor growth and metastatic lung colonization were studied in an experimental tumor model (BALB/c-mouse-sarcoma L-1). Mice
1321537 Blood cultures grew Eikenella corrodens resistant to clindamycin and amikacin. Eikenella corrodens
Human
7498618 In this study the in vitro susceptibility of 1,009 Gram-positive strains isolated from 4,505 positive urocultures was evaluated towards the following chemotherapeutic agents: oxacillin, ampicillin, amoxicillin + clavulanic acid, imipenem, cefalotin, cefotaxime, amikacin, gentamicin, ciprofloxacin, pefloxacin, clindamycin, erythromycin, vancomycin, rifampicin, tetracycline and chloramphenicol. Gram-Positive Bacteria
Human
817663 Effect of clindamycin on the in vitro activity of amikacin and gentamicin against gram-negative bacilli. Escherichia coli
Klebsiella pneumoniae
Pseudomonas aeruginosa
900711 Experiments with rabbits demonstrated no toxic effects on the retina after vitrectomy when the infusion fluid contained either 20 microgram/ml chloramphenicol saline, 10 microgram/ml amikacin saline, 10 microgram/ml tobramycin saline, or 10 microgram/ml clindamycin saline. Rabbits
474606 No significant differences were noted at -20C for clindamycin, chloramphenicol, vancomycin, cefazolin, cephalothin, gentamicin, tobramycin, and amikacin. unknown
7294038 The costs of cefoxitin sodium therapy and clindamycin phosphate plus amikacin sulfate therapy for mixed aerobic-anaerobic infections were compared. Human
7294038 The cost of cefoxitin therapy was significantly less than that of clindamycin plus amikacin therapy and cefoxitin plus amikacin therapy (p less than 0.001) by both pricing methods. unknown
6980839 Twenty-seven isolates of Staphylococcus aureus were found to be resistant to methicillin, nafcillin, tobramycin, gentamicin, amikacin, cefoxitin, clindamycin, erythromycin and chloramphenicol by disc diffusion testing and tube dilution studies; they were sensitive to cefamandole, cephalothin and vancomycin by disc testing. Human
Staphylococcus aureus
6798865 Tobramycin sulfate 160 mg, amikacin sulfate 1 g, ticarcillin disodium 3 g, clindamycin phosphate 300 mg, nafcillin sodium 1 g, and ampicillin sodium was also diluted in plastic bags of 0.9% sodium chloride injection 50 ml. unknown
6446810 The in vitro activity of a unique new 1-oxa cephalosporin beta-lactam antibiotic (LY 127935) was tested against clinical isolates of gram-positive and gram-negative bacteria and compared with the activities of cefoxitin, cefamandole, cephalothin, clindamycin, amikacin, tobramycin, gentamicin, ticarcillin, and carbenicillin. Bacteria
6446810 Against clinical isolates of Pseudomonas species the new compound was more active than cefoxitin, cefamandole, cephalothin, and clindamycin, comparable to ticarcillin and carbenicillin, and less active than gentamicin, tobramycin, and amikacin. unknown
6452816 There was similar activity to penicillin G and clindamycin against anaerobic gram-positive cocci and activity superior to amikacin was demonstrated against Enterobacteriaceae. Enterobacteriaceae
Human
6219865 In vitro activity of moxalactam was compared with the following antibiotics: ampicillin, amikacin, carbenicillin, cefamandole, cefoxitin, cephalothin, chloramphenicol, clindamycin, colistin, erythromycin, gentamicin, oxacillin, penicillin, tetracycline, tobramycin, trimethoprim-sulfamethoxazole and vancomycin. unknown
6197021 On the other hand, all the strains were found by both methods to be susceptible to amikacin, erythromycin, clindamycin and trimethoprim. unknown
3888545 Increased minimum inhibitory concentrations with anaerobiasis for tobramycin, gentamicin, and amikacin, compared to latamoxef, piperacillin, chloramphenicol, and clindamycin. Escherichia coli
Human
Klebsiella
Salmonella
Staphylococcus
Streptococcus
3783303 We measured the stability of vancomycin, amikacin, netilmicin, tobramycin, gentamicin, clindamycin, and aztreonam in an implantable drug pump. Human
3783303 Amikacin, netilmicin, tobramycin, gentamicin, clindamycin, and aztreonam had no effect on the pump and maintained their biologic activity over the 3-week period. unknown
3816545 Compatibility of clindamycin phosphate with amikacin sulfate at room temperature and with gentamicin sulfate and tobramycin sulfate under frozen conditions. Unknown
3816545 The stability and compatibility of clindamycin phosphate with three aminoglycosides, amikacin sulfate, tobramycin sulfate, and gentamicin sulfate, admixed in either glass bottles or plastic bags, were studied under various storage conditions. unknown
3816545 Clindamycin phosphate was admixed with amikacin sulfate in 100 ml glass bottles of both dextrose 5% in water (D5W) and NaCl 0.9%. unknown
3680077 The following antibiotics were tested in concentrations obtained in the serum after standard administration: gentamicin, netilmicin, amikacin, oxacillin, clindamycin, vancomycin, teicoplanin, rifampicin, ansamycin, coumermycin, enoxacin, ciprofloxacin, two new fluoro-quinolones CI 934 and RO 236240, and LY 146032 a new lipopeptidic antibiotic. Human
Staphylococcus aureus
3693645 In six experiments, gentamicin, clindamycin, amikacin, minocin, tylosin, and Linco-Spectin were tested for their effect on motility and fertility of frozen bull spermatozoa and all but clindamycin were used in fertility trials. Unknown
3428140 The stability and compatibility of clindamycin phosphate admixed separately with gentamicin sulfate, tobramycin sulfate, and amikacin sulfate in polypropylene syringes under specific storage conditions were studied. unknown
3428140 In duplicate syringes, clindamycin phosphate 900 mg was admixed with sterile NaCl 0.9% l ml and with either gentamicin sulfate 120 mg, tobramycin sulfate 120 mg, or amikacin sulfate 750 mg. unknown
3428140 For the clindamycin, gentamicin, tobramycin, and amikacin control solutions, changes in concentration were within ten percent of the original concentration. unknown
3428140 Similar results were found with concentrations of clindamycin and amikacin when admixed together. unknown
3312564 The best results were obtained with cefoxitin (4% of infection), metronidazole plus amikacin and latamoxef (8%), while the regimen of clindamycin plus amikacin was associated with the greatest number of complications (20%). Human
3396483 Thus, the cost per day for acquisition/total treatment (in US dollars) are: penicillin $5/$30, gentamicin $1/$46, amikacin $26/$63, clindamycin $38/$57, metronidazole $12/$20 and cefotaxime $47/$60. Unknown
3219747 In reporting on the activity of cephalothin, cefamandole, FCE 22101, gentamicin, netilmicin, amikacin, rifampicin, clindamycin, josamycin, ofloxacin, ciprofloxacin, vancomycin and teicoplanin on 72 Staphylococcus epidermidis strains clinically isolated in the hospital, the Authors observed a high percentage of methicillin-resistance (68.05%) as well as resistance to other important drugs such as gentamicin (72.22%), rifampicin (27.7%), clindamycin (36.1%), and josamycin (40.27%). Human
Staphylococcus epidermidis
3219748 The Authors report microbiological data on the inhibitory activity of cephalothin, cefamandole, FCE 22101, gentamicin, netilmicin, amikacin, rifampicin, clindamycin, josamycin, ofloxacin, ciprofloxacin, vancomycin and teicoplanin against 165 clinically isolated Staphylococcus aureus strains. Human
Staphylococcus aureus
3219748 The activity of the tested drugs was good; the presence of nosocomial strains resistant to rifampicin (12.13%), clindamycin (13.94%), josamycin (18.2%), ofloxacin (4.85%), ciprofloxacin (12.7%), gentamicin (27.3%), amikacin (9.7%), netilmicin (7.9%) was noted. unknown
3223655 All isolates were susceptible to cephalothin, clindamycin, chloramphenicol, gentamicin, kanamycin, and amikacin. Goats
Staphylococcus aureus
2896693 Of these 78% were resistant to penicillin, 50% to methicillin at 37 degrees C, 62% to methicillin at 30 degrees C, 38% to erythromycin, 32% to tobramycin, 15% to clindamycin, 15% to fusidic acid, 9% to amikacin, 5% to netilmicin and 0% to vancomycin. unknown
2725399 Nationally, the prevalence of resistance was 85.3% to penicillin G, 14.4% to methicillin, 14.0% to amoxycillin/clavulanate, 9% to cephalothin, 5.4% to cephamandole, 9.9% to cefotaxime, 25.0% to erythromycin, 11.2% to clindamycin, 21.7% to tetracycline, 13.0% to gentamicin, 1.9% to amikacin, 5.8% to chloramphenicol, 18.3% to trimethoprim, 0.6% to rifampicin, 3.0% to fusidic acid and 1.2% to novobiocin. Human
Staphylococcus aureus
3468319 In vitro activity of imipenem was compared with the following antibiotics: ampicillin, amikacin, carbenicillin, cefoperazone, cefoxitin, cephalothin, chloramphenicol, clindamycin, colistin, erythromycin, gentamicin, methicillin, penicillin, tetracycline, tobramycin, trimethoprim-sulfamethoxazole and vancomycin. Gram-Negative Bacteria
Gram-Positive Bacteria
3104277 Susceptibilities of 28 strains of Pseudomonas aeruginosa, 32 strains of Enterobacteriaceae and 24 strains of Staphylococcus aureus were tested against combinations of enoxacin with either cefsulodin, piperacillin, or amikacin, enoxacin with either aztreonam, latamoxef or amikacin, and enoxacin with either oxacillin, clindamycin or vancomycin, respectively. unknown
3477333 Minimum inhibitory (MIC) and minimum bactericidal (MBC) concentrations of imipenem, pefloxacin, BMY 28142, were compared with those of vancomycin and other established antistaphylococcal antimicrobial agents, rifampicin, fusidic acid, clindamycin, tobramycin and amikacin against 50 clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). Staphylococcus aureus
2190015 A 3 arm prospective randomized trial was designed to compare the effectiveness of aztreonam (AZT) + clindamycin (CLDM), amikacin (AMK) + AZT and CLDM + AMK as antibiotic therapy for fever in patients with hematological disorders. Human
2190015 Efficacy rates were 64.2% in the AZT + CLDM group, 52.8% in the AMK + AZT group and 35.2% in the CLDM + AMK group. unknown
2124539 Ampicillin, penicillin, azlocillin, imipenem, gentamicin, netilmicin, amikacin, erythromycin, rifampicin, trimethoprim, clindamycin and vancomycin had good activity, while cephalothin, chloramphenicol, ciprofloxacin and ofloxacin were less active, and cefuroxime, enoxacin, norfloxacin and fosfomycin were the least active. Listeria monocytogenes
2070756 The Staphylococcus aureus was 100% sensitive to Augmentin (Amoxicillin plus clavulinic acid), Clindamycin, Novobiocin, and Amikacin while the gram negative bacilli were sensitive to Cefotaxime, Piperacillin, Amikacin and augmentin, Clindamycin, Chloramphenicol and Lincomycin inhibited the growth of anaerobes to a varying degree. Human
1875230 Comparative efficacy of cefotetan and clindamycin plus amikacin as antimicrobial prophylaxis for major head and neck surgery. Human
1875230 A total of 41 patients were randomly allocated to receive either cefotetan (total dose, 20 g) or clindamycin (total dose, 12 g) plus amikacin (total dose, 5 g) as perioperative antimicrobial prophylaxis for major head and neck surgery. unknown
1875230 The wound infection rate was 4% in the group of patients receiving cefotetan and 0% in the group receiving clindamycin plus amikacin. unknown
1880915 Clinical effects of combined use of aztreonam (AZT), amikacin (AMK) and clindamycin (CLDM) in 46 cases with infectious diseases in obstetrics and gynecology were retrospectively studied in 2 groups, and the following results were obtained. Human
1880915 No significant difference in efficacy rates was noted between AZT plus CLDM treated group (n = 25) and AMK plus CLDM treated group (n = 21) (96.0% vs. 95.2%), while rate of excellent efficacy was slightly higher in AZT plus CLDM group than AMK plus CLDM group (24.0% vs. 14.3%). unknown
1889177 These activities were generally superior to that of ciprofloxacin, imipenem, ampicillin, penicillin G, oxacillin, cefazolin, ceftazidime, cefoxitin, cefsulodin, aztreonam, piperacillin, amikacin, spectinomycin, doxycycline, erythomycin, clindamycin, metronidazole, and vancomycin. Bacteria
Human
1503590 Fever abated 48 hours after initiating two weeks of therapy with intravenous Clindamycin and Amikacin. Human
1507454 The strains showed resistance ranging from 20% to 80%, to 10 agents, such as amikacin, chloramphenicol, clindamycin, gentamicin, neomycin, streptomycin, tobramycin, acriflavine, cadmium nitrate, ethidium bromide. unknown
1416895 Antimicrobial prophylaxis for major head and neck surgery in cancer patients: sulbactam-ampicillin versus clindamycin-amikacin. Human
1416895 A total of 99 patients with head and neck cancer who were to undergo surgery were randomized in a prospective comparative study of sulbactam-ampicillin (1:2 ratio; four doses of 3 g of ampicillin and 1.5 g of sulbactam intravenously [i.v.] every 6 h) versus clindamycin (four doses of 600 mg i.v. every 6 h)-amikacin (two doses of 500 mg i.v. every 12 h) as prophylaxis starting at the induction of anesthesia. unknown
1416895 The two groups of evaluable patients (43 in the clindamycin-amikacin treatment group and 42 in the sulbactam-ampicillin treatment group) were comparable as far as age (mean, 57 years; range, 21 to 84 years), sex ratio (71 males, 28 females), weight (mean, 66 kg; range, 40 to 69 kg), indication for surgery (first surgery, 48 patients; recurrence, 37 patients), previous anticancer treatment (surgery, radiation therapy, chemotherapy), type of surgery, and stage of cancer. unknown
1416895 Wound infections occurred in 14 (33%) sulbactam-ampicillin-treated patients and 9 (21%) clindamycin-amikacin-treated patients (P = 0.19; not significant). unknown
1416895 Antimicrobial treatment was required within 20 days after surgery for 42% of the sulbactam-ampicillin-treated patients and 44% of the clindamycin-amikacin-treated patients.(ABSTRACT TRUNCATED AT 250 WORDS) unknown
8451711 This organism was resistant to sulphafurazole, trimethoprim, nalidixic acid, cefazolin, nitrofurantoin, clindamycin, erythromycin, oxacillin, penicillin, gentamicin, amikacin, cinoxacin, ceftazidime and cefotaxime, but was susceptible to ciprofloxacin, ofloxacin, norfloxacin, vancomycin and fucidin. Human
8452190 The combination of fleroxacin with such aminoglycosides as gentamicin, amikacin, and tobramycin is indifferent against most Enterobacteriaceae, as is the combination of fleroxacin with penicillins, cephalosporins, rifampin, clindamycin, and metronidazole. Bacteria
8468114 Amikacin was used alone or in combination with metronidazole, clindamycin, fosfomycin or a beta-lactam. Human
8373850 Antimicrobial susceptibility testing revealed that most of the Salmonella isolates were sensitive to a variety of antimicrobials, particularly amikacin and apramycin, and resistant to some others, such as clindamycin, erythromycin, penicillin, and sulfadimethoxine. Dogs
Salmonella
8104211 The effect of two polyurethane ['Cavafix Certo' (CAV); 'Viacath' (VIA)] catheters on the in-vitro activity of amikacin (AN), clindamycin (CM), cloxacillin (CX), ciprofloxacin (CIP), vancomycin (VA), teicoplanin (TEI) and daptomycin (DAP) against slime producing and non-producing Staphylococcus epidermidis strains was determined using a microdilution assay. Human
Staphylococcus epidermidis
8289214 The activity of a high concentration (16 x MBC) of these antimicrobial agents against S. epidermidis biofilms in Teflon catheters was evaluated; for five slime non-producing strains, the highest reduction (around 99%) in bacterial viability was produced by cloxacillin and teicoplanin; for the slime producers, the highest effect (99.5% reduction) was shown by amikacin, clindamycin cloxacillin and ciprofloxacin but all cases still showed bacterial counts higher than 10(3) cfu/catheter segment. Human
Staphylococcus epidermidis
8023265 Clindamycin plus amikacin versus clindamycin plus aztreonam in established intraabdominal infections. Human
8023265 A prospective, randomized, single-blind study evaluated the efficacy and safety of clindamycin plus amikacin versus clindamycin plus aztreonam (Cl-Az) in treating intraabdominal infections in adults. unknown
8023265 Patients were treated intravenously for 7 to 10 days, clindamycin 900 mg plus amikacin 5.0 mg/kg three times a day or clindamycin 900 mg plus aztreonam 2.0 gm three times a day. unknown
8023265 On therapy completion, clinical and bacteriologic responses were as follows: clindamycin plus amikacin group, 26 (84%) cured, 3 (9.7%) improved, and 2 (6.3%) failed; Cl-Az group, 25 (80.7%) cured, 6 (19.3%) improved, and 0 failed. unknown
8996735 Its inhibitory activity was slightly superior or comparable to that of other fluoroquinolones tested, namely ciprofloxain and norfloxain, and significantly greater than the conventional drugs, such as amikacin, ampicillin, Augmentin, ceftazidime, clindamycin, tetracycline and trimethoprim-sulfamethoxazole, used in the treatment of typhoid fever. Salmonella typhi
8307143 All 288 MRSA isolates were sensitive to vancomycin and pristinomycin; 98.6% were sensitive to fucidine; 97.9% to imipenem; 79% to rifampicin; 63.6% to amikacin; 54.5% to augmentin; 36.4% to clindamycin; 12.6% to ciprofloxacin; 11.9% to cotrimoxazole and ofloxacin; 10.5% to gentamicin; 9.8% to erythromycin; and 8.4% to norfloxacin. Human
Staphylococcus aureus
7859856 The following antibiotics were tested: penicillin G, ampicillin, amoxicillin, piperacillin, imipenem, oxacillin, ofloxacin, pefloxacin, ciprofloxacin, gentamicin, tobramycin, amikacin, netilmicin, rifampicin, clindamycin, tetracycline, cotrimoxazole, erythromycin, chloramphenicol, vancomycin and teicoplanin. Enterococcus
Human
Staphylococcus
7574529 In the macrophage cell line assay, CRL8131 produced a synergistic effect on intracellular killing of M. tuberculosis by isoniazid, rifampin, streptomycin, pyrazinamide, thiacetazone, D-cycloserine, ethionamide, amikacin, clindamycin, and p-aminosalicylic acid. unknown
8564608 Each cefpirome sulfate solution was mixed 1:1 (simulating Y-site injection) with amikacin 5.0 mg/mL (as the sulfate salt), amphotericin B 0.1 mg/mL, cefazolin 10 mg/mL (as the sodium salt), clindamycin 12.0 mg/mL (as the phosphate ester), dexamethasone phosphate 4.0 mg/mL (as the sodium salt), dopamine hydrochloride 0.8 mg/mL, epinephrine 0.1 mg/mL (as the hydrochloride salt), fluconazole 2.0 mg/mL, gentamicin 1.0 mg/mL (as the sulfate salt), and vancomycin 5.0 mg/mL (as the hydrochloride salt). unknown
9499892 In I group (75 sinuses) into sinus has been given clindamycin, in II group (56 sinuses) clindamycin, gentamycin or amikacin with metronidazol, in III group (comparative) others antibiotics. Human
8996735 Its inhibitory activity was slightly superior or comparable to that of other fluoroquinolones tested, namely ciprofloxain and norfloxain, and significantly greater than the conventional drugs, such as amikacin, ampicillin, Augmentin, ceftazidime, clindamycin, tetracycline and trimethoprim-sulfamethoxazole, used in the treatment of typhoid fever. Salmonella typhi
9548431 Over a one-year period, all coagulase-negative staphylococci (CoNS) from blood cultures, cerebrospinal fluids and peritoneal effluents from patients in a major Danish university hospital were investigated for susceptibility to penicillin G; methicillin; gentamicin; netilmicin; amikacin; erythromycin; clindamycin; fusidic acid; rifampicin; tetracycline; chloramphenicol; ciprofloxacin; teicoplanin; and vancomycin. Human
Staphylococcus
9596854 The placental transfer of amikacin, clindamycin and erythromycin was slightly higher than beta-lactams. unknown
9571661 PATIENTS AND METHODS: The time-kill profiles of four endophthalmitis isolates of Enterococcus faecalis, one vancomycin-resistant E. faecalis isolate, and three vancomycin-resistant isolates of E. faecium were determined against vancomycin, amikacin, cefazolin, gentamicin, ampicillin, ciprofloxacin, ceftazidime, clindamycin, and the combinations of vancomycin and amikacin, vancomycin and ceftazidime, vancomycin and gentamicin, vancomycin and ampicillin, cefazolin and gentamicin, and ampicillin and gentamicin. Enterococcus faecalis
Enterococcus faecium
Human
9674160 All other isolates were resistant to cefoxitin (30 micrograms), aztreonam (30 micrograms), vancomycin (30 micrograms), amikacin (30 micrograms), gentamicin (10 micrograms), kanamycin (30 micrograms), streptomycin (10 micrograms), fusidic acid (10 micrograms), trimethoprim (5 micrograms), norfloxacin (10 micrograms), nalidixic acid (30 micrograms), metronidazole (5 micrograms), polymyxin B (300 micrograms) and colistin sulphate (10 micrograms), and they were susceptible to the six penicillins studied, cephalothin (30 micrograms), cefuroxime (30 micrograms), cefaclor (30 micrograms), ceftizoxime (30 micrograms), cefotaxime (30 micrograms), bacitracin (10 micrograms), chloramphenicol (30 micrograms), erythromycin (15 micrograms), clindamycin (2 micrograms), rifampicin (5 micrograms) and nitrofurantoin (300 micrograms). Bifidobacterium
Human
9760790 Strains of Staphylococcus aureus were sensitive mainly to amoxycillin--clavulanic acid, roxitromycin, amikacin, netilmicin, clindamycin, cefamandol, chloramphenicol, rifampicin and resistant mostly to penicillin /90% of strains/, ampicillin, tetracyclines. Human
9769668 Concentrations of gentamicin, amikacin, streptomycin, ceftriaxone, benzylpenicillin, clindamycin and lincomycin were measured in serum of 110 patients by microbiological agar cup method. Escherichia coli
Human
Staphylococcus aureus
9872079 In this study, we examined the effects of antibiotics on chemotaxis and phagocytosis by reacting macrophages with 7 different antibiotics, specifically ampicillin (ABPC), cephalexin (CEX), cefotiam (CTM), amikacin (AMK), clindamycin (CLDM), tetracycline (TC) and bleomycin (BLM). Rats
9809600 The gram-negative bacteria were most susceptible to amikacin (91% of 91 isolates) and least susceptible to clindamycin (3% of 109 isolates). unknown
10222843 Severe infection--combination therapy consisting of two antibiotics: one with activity against Gram positive bacteria such as cloxacillin, erythromycin, cefazolin, cephalexin, clindamycin--the other with activity against Gram negative bacteria, such as aminoglycoside (e.g., netilmicin, amikacin) or third generation cephalosporine (e.g., cefotaxime, ceftriaxone). unknown
10454948 Use of all antimicrobial agents except clindamycin and amikacin was significantly reduced. Enterococcus
Human
10503274 Intravitreal vancomycin and amikacin and intravenous penicillin and clindamycin were given. Human
10582879 A still lower concentration, 0.1 microg/ml, produced synergistic enhancement of the activities of clarithromycin, rifampin, amikacin, streptomycin, and clindamycin, but not isoniazid, against MAI infecting monocytoid cells. Human
Mice
11126812 The discs used were ampicillin, trimethoprim-sulfamethoxazole, cefotaxime, ceftriaxone, aztreonam, ofloxacin, carbenicillin, amikacin, gentamicin, penicillin, clindamycin, methicillin, vancomycin, ceftazidime, cefuroxime, Nalidixic acid, pipemedic acid and Nitrofurantoin. Unknown