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Ali, Nawab
Baltosser, William H
Bayrak, Coskun
Beger, Richard
Benes, Helen
Berleant, Dan
Bowyer, John F
Bruhn, Russel
Bush, John
Chan, Yupo
Chiang, Chia-Chu
Compadre, Cesar
Dagtas, Serhan
Mock, Donald
Nagarajan, Radhakris
Patterson, Tucker
Pidugu, Srikanth B
Pierce, Elizabeth M
Preissl, Hubert T
Ramaswamy, Srinivasa
Reis, Robert J S
Seker, Remzi
Simpson, Pippa
Slikker, William
Soulsby, Sr., Michae
Suva, Larry
Tang, Peiyi
Thompson, Gary A
Tong, Weida
Tudoreanu, M Eduard
Vanbiervliet, Alan G
Wigand, Rolf T
Xu, Xiaowei
Zhang, Jianjun
Zhou, Yi-Hong
Darsey, Jerry A
Elsalloukh, Hassan
Epstein, Joshua
Eswaran, Hari
Fuscoe, James C
Gealt, Michael A
Govindan, Rathinaswa
Gray, Wayne L
He, Qingfang
Iqbal, Kamran
Jennings, Steven F
Jo, Chan-Hee
Kane, Cynthia (Cindy
Kaufmann, Eric R
Kieber-Emmons, Thoma
Light, Kim
Liu, Xian
Lowery, Curtis L
Luba, James
Ma, Xiaodong
Milanova, Mariofanna
Ounpraseuth, Songthi
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Dr. James C Fuscoe
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Director, Center for Functional Genomics of Division of Systems Toxicology
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| Affiliation |
UALR NCTR |
| Office |
NCTR, 53E-119 |
| Email |
jfuscoe AT nctr.fda.gov |
| Website |
http:// |
| Phone |
870-543-7126 |
| Fax |
870-543-7682 |
| Mail |
3900 NCTR Rd., HFT-130
Jefferson, Arkansas 72079 |
| Core Areas |
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| Research Areas |
Dr. James Fuscoe has been involved in developing and utilizing biotechnology in the understanding of cancer and other diseases for more than 25 years. His studies have included some of the first publications on DNA characterization of genetic defects in mammalian cell selectable marker genes, the construction of a complete set of human chromosome-specific gene libraries for application to human diseases, development of the widely used fluorescence in situ hybridization (FISH) technique for mapping, analysis of chromosomal defects, and novel PCR methods for quantitative analysis of mutations. Most recently, he has established a microarray center at NCTR for toxicogenomics research. Dr. Fuscoe has authored or co-authored more than 65 peer-reviewed publications applying molecular genetic approaches to development and application of molecular biomarkers to detect effects of drug exposures, mammalian molecular genetics, and mutagenesis / carcinogenesis. Students working in Dr. Fuscoe’s laboratory may expect to be involved in projects related to toxicogenomics, utilizing microarray technology and functional genomic approaches to understand mechanisms of toxicity and to develop biomarkers of exposure and effect. Strong collaborations exist with the statistics and toxicoinformatics departments at NCTR and joint projects can be developed incorporating toxicology, functional genomics technology, and bioinformatics.
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